Respir Res:母乳喂养时间能够改变新生儿和家族风险因素对儿童哮喘和过敏的影响

2021-02-24 AlexYang MedSci原创

儿童哮喘和过敏性疾病是一个严重的全球性问题。关于分娩方式、家庭中孩子的数量和母乳喂养与儿童哮喘和过敏性疾病的关联性发现并不一致。最近,有研究人员评估了这些关联,并调查了母乳喂养是否改变了新生儿和家族性

儿童哮喘和过敏性疾病是一个严重的全球性问题。关于分娩方式、家庭中孩子的数量和母乳喂养与儿童哮喘和过敏性疾病的关联性发现并不一致。最近,有研究人员评估了这些关联,并调查了母乳喂养是否改变了新生儿和家族性风险因素对儿童哮喘和过敏性疾病的影响

研究人员在中国上海进行了一项基于人群的横断面研究,并从上海13个区随机选取17所小学。结果表明,在10464名6-11岁的小学生中,儿童哮喘、过敏性鼻炎、荨麻疹、食物过敏和药物过敏的总患病率分别为13.9%、22.7%、15.3%、8.1%和4.6%。男性、高社会经济地位、剖腹产、家庭中只有一个孩子和有过敏家族史与儿童哮喘和过敏性疾病的几率增加有关,而较长的母乳喂养时间(>6个月)与这些疾病呈负相关关系。较长的母乳喂养时间也减弱了新生儿和家族性风险因素对儿童哮喘和过敏性疾病的OR。例如,阴道分娩和母乳喂养持续时间>6个月组的儿童哮喘调整后的OR最低(0.78,95%CI:0.66,0.92)。

最后,研究人员指出,较长的母乳喂养时间与儿童哮喘和过敏性疾病发生成反比,同时也降低了新生儿和家族性风险因素对这些疾病的影响。鉴于儿童哮喘和过敏性疾病的发病率在全球范围内迅速上升,他们的发现可能具有重要的临床和公共卫生意义。

原始出处:

Yabin Hu , Yiting Chen , Shijian Liu et al. Breastfeeding duration modified the effects of neonatal and familial risk factors on childhood asthma and allergy: a population-based study. Respir Res. Feb 2021

 

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    2021-02-26 villahu
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    2021-02-25 ms5000000899056107

    长知识了

    0

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    2021-02-25 ms5000000899056107

    学习了

    0

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