JAMA Neurol:他汀类药物可降低脑震荡老人后续痴呆风险

2019-05-29 MedSci MedSci原创

研究发现,他汀类药物可降低脑震荡老人后续痴呆风险

脑震荡是一种急性损伤,可能导致慢性残疾,而使用他汀类药物可能有助于神经系统的恢复。近日研究人员考察了他汀类药物对脑震荡后痴呆风险的影响。

研究于1993年4月1日至2013年4月1日在加拿大安大略省开展。参与者为脑震荡的老年,在脑震荡后90天内服用他汀类药物。研究的主要终点为痴呆的长期发病率。

28815名诊断为脑震荡的患者(中位年龄76岁,女性61.3%),其中7058人(24.5%)接受了他汀类药物治疗,21757人(75.5%)未接受他汀类药物治疗。在3.9年的平均随访中,共有4727名患者随后发展为痴呆,每6名参与者中1例的发病。与未服用他汀类药物的患者相比,接受他汀类药物的患者患痴呆风险降低了13%(相对风险为0.87),且与其他血管药物使用无关。

研究发现,他汀类药物可降低脑震荡老人后续痴呆风险。

原始出处:

Donald A. Redelmeier et al. Association Between Statin Use and Risk of Dementia After a Concussion. JAMA Neurol. May 20 2019.

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    2019-12-09 yinhl1978
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    2019-05-31 TZF0804
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    2019-05-29 junJUN

    老年人痴呆何药可用??

    0

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