Heart:心包脂肪含量与HIV患者不良的心功能相关

2019-12-29 不详 MedSci原创

艾滋病毒携带者(PLHIV)改变了脂肪分布,增加了心力衰竭的风险,在这个人群中,心脏周围脂肪的数量和放射密度的改变是否与心功能不全有关尚不清楚。本研究的目的旨在评估HIV患者的心包脂肪(PCF)与心脏功能的相关性。本研究纳入分析了100例年龄>45岁且存在>1个传统心血管危险因素的HIV患者和100年龄和性别匹配的对照。与对照相比,PLHIV患者的BMI更低(27 vs 30, p=0.02),糖

艾滋病毒携带者(PLHIV)改变了脂肪分布,增加了心力衰竭的风险,在这个人群中,心脏周围脂肪的数量和放射密度的改变是否与心功能不全有关尚不清楚。本研究的目的旨在评估HIV患者的心包脂肪(PCF)与心脏功能的相关性。

本研究纳入分析了100例年龄>45岁且存在>1个传统心血管危险因素的HIV患者和100年龄和性别匹配的对照。与对照相比,PLHIV患者的BMI更低(27 vs 30, p=0.02),糖尿病率也更低(26% vs 45%, p=0.005),平均的左室射血分数为67%。在经传统心血管危险因素调整分析后,HIV与更高的左室质量指数(LVMI)相关(95%?CI 3.22 -17.4; p=0.005),与更差的左室整体纵向应变相关(95%?CI :-1.66- -0.07; p=0.03),与更高的舒张功能不全相关(OR 1.96; 95%?CI 0.95-4.06; p=0.07)。另外,PCF体积明显与更高的LVMI和更差的左室整体纵向应变相关。

研究结果显示,在HIV携带者中,心包脂肪含量明显与不良的心脏功能相关。

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    2019-12-31 zhaojie88
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    2019-12-31 slcumt
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2003369, encodeId=4cc0200336904, content=<a href='/topic/show?id=5012890397' target=_blank style='color:#2F92EE;'>#HIV患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8903, encryptionId=5012890397, topicName=HIV患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b505306, createdName=医生2394, createdTime=Tue Sep 22 16:58:00 CST 2020, time=2020-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357347, encodeId=a3ad135e347aa, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465692, encodeId=4216146569220, content=<a href='/topic/show?id=5f5f508933f' target=_blank style='color:#2F92EE;'>#心功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50893, encryptionId=5f5f508933f, topicName=心功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6df96750284, createdName=caobinglei8081, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563194, encodeId=651d156319400, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591097, encodeId=1c43159109e6d, content=<a href='/topic/show?id=d64a50920ad' target=_blank style='color:#2F92EE;'>#心包脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50920, encryptionId=d64a50920ad, topicName=心包脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=edc717907637, createdName=lilianxiang, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377596, encodeId=60b13e759662, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Mon Dec 30 18:27:55 CST 2019, time=2019-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377562, encodeId=ab583e7562f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Dec 29 18:24:37 CST 2019, time=2019-12-29, status=1, ipAttribution=)]
    2019-12-30 一个字-牛

    学习了谢谢分享

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2003369, encodeId=4cc0200336904, content=<a href='/topic/show?id=5012890397' target=_blank style='color:#2F92EE;'>#HIV患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8903, encryptionId=5012890397, topicName=HIV患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b505306, createdName=医生2394, createdTime=Tue Sep 22 16:58:00 CST 2020, time=2020-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357347, encodeId=a3ad135e347aa, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465692, encodeId=4216146569220, content=<a href='/topic/show?id=5f5f508933f' target=_blank style='color:#2F92EE;'>#心功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50893, encryptionId=5f5f508933f, topicName=心功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6df96750284, createdName=caobinglei8081, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563194, encodeId=651d156319400, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591097, encodeId=1c43159109e6d, content=<a href='/topic/show?id=d64a50920ad' target=_blank style='color:#2F92EE;'>#心包脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50920, encryptionId=d64a50920ad, topicName=心包脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=edc717907637, createdName=lilianxiang, createdTime=Tue Dec 31 05:58:00 CST 2019, time=2019-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377596, encodeId=60b13e759662, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Mon Dec 30 18:27:55 CST 2019, time=2019-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377562, encodeId=ab583e7562f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Dec 29 18:24:37 CST 2019, time=2019-12-29, status=1, ipAttribution=)]
    2019-12-29 天地飞扬

    了解

    0

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