NeuroImage:戴口罩对fMRI BOLD的影响

2021-06-23 MedSci原创 MedSci原创

佩戴口罩进行梯度回波功能磁共振成像可以改变BOLD基线信号,但对任务激活的影响很小。

由于新型冠状病毒SARS-CoV-2的国际传播,许多MRI扫描设备要求扫描对象在扫描时戴上面罩,以防止病毒传播。其主要目的是控制可携带病毒的呼吸道飞沫,避免它们降落在物体表面或停留在空气中,可能感染他人。口罩有多种类型(CDC, 2020),从布口罩和外科手术口罩到N95呼吸器,都有不同程度的保留一个或多个呼吸周期的呼出空气。因为戴上口罩,将呼出的空气与吸入的气流混合,吸入的二氧化碳浓度会升高,导致轻度高碳酸血症。已证实,吸入混合气的变化会改变R2加权血氧依赖(BOLD)对比。 既然CO2是一种有效的血管扩张剂,CO2的升高是否会改变功能MRI (fMRI)? NeuroImage杂志发表研究论文研究了面孔掩蔽在刺激视觉、听觉和感觉运动皮层的感觉运动任务中改变BOLD对比的潜力。 利用鼻导管向戴着手术口罩的受试者提供空气在90s的开合间隔内置换呼出的二氧化碳,同时受试者执行感觉运动任务。 上图显示了在有和没有口罩的情况下,单受试者对感觉运动任务和空气开关区域的激活结果。图A、B中集中于视觉、听觉和感觉运动皮层的任务激活,无论有无口罩,都保持强劲。激活掩码任务和不激活掩码任务之间的区别(

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    2021-06-24 121e4046m22(暂无昵称)

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1936967, encodeId=e5d8193696e51, content=<a href='/topic/show?id=ba0354191e3' target=_blank style='color:#2F92EE;'>#戴口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54191, encryptionId=ba0354191e3, topicName=戴口罩)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Tue May 10 12:41:03 CST 2022, time=2022-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307889, encodeId=a7cb130e8899e, content=<a href='/topic/show?id=2be638263f4' target=_blank style='color:#2F92EE;'>#口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38263, encryptionId=2be638263f4, topicName=口罩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Fri Jun 25 14:41:03 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976451, encodeId=35089e64513f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2dfe2289990, createdName=121e4046m22(暂无昵称), createdTime=Thu Jun 24 09:04:44 CST 2021, time=2021-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976445, encodeId=bfc79e6445f7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=592a5441263, createdName=素馨飘零, createdTime=Thu Jun 24 08:51:31 CST 2021, time=2021-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976408, encodeId=0a839e6408d4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=faae5295647, createdName=148728e5m16暂无昵称, createdTime=Thu Jun 24 06:15:12 CST 2021, time=2021-06-24, status=1, ipAttribution=)]
    2021-06-24 素馨飘零

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1936967, encodeId=e5d8193696e51, content=<a href='/topic/show?id=ba0354191e3' target=_blank style='color:#2F92EE;'>#戴口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54191, encryptionId=ba0354191e3, topicName=戴口罩)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Tue May 10 12:41:03 CST 2022, time=2022-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307889, encodeId=a7cb130e8899e, content=<a href='/topic/show?id=2be638263f4' target=_blank style='color:#2F92EE;'>#口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38263, encryptionId=2be638263f4, topicName=口罩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Fri Jun 25 14:41:03 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976451, encodeId=35089e64513f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2dfe2289990, createdName=121e4046m22(暂无昵称), createdTime=Thu Jun 24 09:04:44 CST 2021, time=2021-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976445, encodeId=bfc79e6445f7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=592a5441263, createdName=素馨飘零, createdTime=Thu Jun 24 08:51:31 CST 2021, time=2021-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976408, encodeId=0a839e6408d4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=faae5295647, createdName=148728e5m16暂无昵称, createdTime=Thu Jun 24 06:15:12 CST 2021, time=2021-06-24, status=1, ipAttribution=)]
    2021-06-24 148728e5m16暂无昵称

    学习了

    0

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