Stroke:颈动脉夹层合并肌纤维发育不良患者的临床特征

2021-03-07 MedSci原创 MedSci原创

观察性研究表明肌纤维发育不良与自发性颈动脉夹层(sCeAD)有关。然而,这两种疾病并存的患者是否具有鲜明的临床特征尚未得到广泛的研究。

观察性研究表明肌纤维发育不良与自发性颈动脉夹层(sCeAD)有关。然而,这两种疾病并存的患者是否具有鲜明的临床特征尚未得到广泛的研究。

近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员从2000年1月至2019年6月期间完成的多中心IPSYS CeAD研究(意大利青少年成人颈动脉夹层卒中项目)中招募了首次sCeAD患者组成队列,并比较同时共存有脑血管肌纤维发育不良(cFMD; cFMD+)患者与无cFMD患者(cFMD-)的人口和临床特点、危险因素、血管病理、中期结局。

该研究共纳入了1283例符合分析要求的sCeAD患者(平均年龄为47.8±11.4岁;女性有545人(42.5%)),其中103人(8.0%)被诊断为cFMD+。在多变量分析中,有偏头痛史(比值比为1.78 [95%CI为1.13-2.79])、伴有颅内动脉瘤(比值比为8.71 [95%CI为4.06-18.68])和事件发生前轻微外伤(比值比为0.48 [95%CI为0.26-0.89])与cFMD相关。

在中位随访34.0个月(25-75百分位为60.0)后,39例(3.3%)患者出现了复发性sCeAD事件。在多变量Cox比例风险分析中,cFMD+和偏头痛史可以独立预测sCeAD的复发风险(风险比分别为3.40和2.07,95%CI分别为1.58-7.31和1.06-4.03)。

由此可见,sCeAD合并cFMD的患者与无cFMD患者的危险因素有所不同。cFMD和偏头痛是sCeAD患者中期复发风险的独立预测因素

原始出处:

Sonia Bonacina.et al.Clinical Features of Patients With Cervical Artery Dissection and Fibromuscular Dysplasia.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.031579

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createdBy=920c231, createdName=lixiaol, createdTime=Wed Sep 15 10:04:14 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804475, encodeId=30ae18044e567, content=<a href='/topic/show?id=82ade7236c8' target=_blank style='color:#2F92EE;'>#纤维发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77236, encryptionId=82ade7236c8, topicName=纤维发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Thu Feb 10 06:04:14 CST 2022, time=2022-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1842968, encodeId=5575184296842, content=<a href='/topic/show?id=112222886b8' target=_blank style='color:#2F92EE;'>#临床特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22886, encryptionId=112222886b8, topicName=临床特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Apr 30 16:04:14 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078054, encodeId=e4be20e8054be, content=<a href='/topic/show?id=8a8580960a5' target=_blank style='color:#2F92EE;'>#肌纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80960, encryptionId=8a8580960a5, topicName=肌纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Wed Sep 08 04:04:14 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927045, encodeId=d5c5192e04535, content=<a href='/topic/show?id=6b57100540e2' target=_blank style='color:#2F92EE;'>#颈动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100540, encryptionId=6b57100540e2, topicName=颈动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6eba113, createdName=xiaoyeshuang, createdTime=Sun May 09 05:04:14 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960517, encodeId=c25e96051eb3, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78415486317, createdName=ms7000001791696491, createdTime=Mon Apr 26 02:19:50 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=946904, encodeId=e7bc94690411, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习到很多新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210307/b75ef807ee37426488262434e88f2054/ddba9eab8dcf4ab582aa531cff52c0a8.jpg, createdBy=f7cf2444395, createdName=小希言, createdTime=Tue Mar 09 21:01:39 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347533, encodeId=3164134e5332e, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1843613, encodeId=d1fb184361375, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Tue Aug 03 14:04:14 CST 2021, time=2021-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928847, encodeId=e311192884efe, content=<a href='/topic/show?id=80c480961a5' target=_blank style='color:#2F92EE;'>#肌纤维发育不良#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80961, encryptionId=80c480961a5, topicName=肌纤维发育不良)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Wed Sep 15 10:04:14 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804475, encodeId=30ae18044e567, content=<a href='/topic/show?id=82ade7236c8' target=_blank style='color:#2F92EE;'>#纤维发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77236, encryptionId=82ade7236c8, topicName=纤维发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Thu Feb 10 06:04:14 CST 2022, time=2022-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1842968, encodeId=5575184296842, content=<a href='/topic/show?id=112222886b8' target=_blank style='color:#2F92EE;'>#临床特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22886, encryptionId=112222886b8, topicName=临床特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Apr 30 16:04:14 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078054, encodeId=e4be20e8054be, content=<a href='/topic/show?id=8a8580960a5' target=_blank style='color:#2F92EE;'>#肌纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80960, encryptionId=8a8580960a5, topicName=肌纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Wed Sep 08 04:04:14 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927045, encodeId=d5c5192e04535, content=<a href='/topic/show?id=6b57100540e2' target=_blank style='color:#2F92EE;'>#颈动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100540, encryptionId=6b57100540e2, topicName=颈动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6eba113, createdName=xiaoyeshuang, createdTime=Sun May 09 05:04:14 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960517, encodeId=c25e96051eb3, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78415486317, createdName=ms7000001791696491, createdTime=Mon Apr 26 02:19:50 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=946904, encodeId=e7bc94690411, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习到很多新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210307/b75ef807ee37426488262434e88f2054/ddba9eab8dcf4ab582aa531cff52c0a8.jpg, createdBy=f7cf2444395, createdName=小希言, createdTime=Tue Mar 09 21:01:39 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347533, encodeId=3164134e5332e, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
    2021-09-08 okhuali
  6. [GetPortalCommentsPageByObjectIdResponse(id=1843613, encodeId=d1fb184361375, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Tue Aug 03 14:04:14 CST 2021, time=2021-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928847, encodeId=e311192884efe, content=<a href='/topic/show?id=80c480961a5' target=_blank style='color:#2F92EE;'>#肌纤维发育不良#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80961, encryptionId=80c480961a5, topicName=肌纤维发育不良)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encryptionId=112222886b8, topicName=临床特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Apr 30 16:04:14 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078054, encodeId=e4be20e8054be, content=<a href='/topic/show?id=8a8580960a5' target=_blank style='color:#2F92EE;'>#肌纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80960, encryptionId=8a8580960a5, topicName=肌纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Wed Sep 08 04:04:14 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927045, encodeId=d5c5192e04535, content=<a href='/topic/show?id=6b57100540e2' target=_blank style='color:#2F92EE;'>#颈动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100540, encryptionId=6b57100540e2, topicName=颈动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6eba113, createdName=xiaoyeshuang, createdTime=Sun May 09 05:04:14 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960517, encodeId=c25e96051eb3, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78415486317, createdName=ms7000001791696491, createdTime=Mon Apr 26 02:19:50 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=946904, encodeId=e7bc94690411, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习到很多新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210307/b75ef807ee37426488262434e88f2054/ddba9eab8dcf4ab582aa531cff52c0a8.jpg, createdBy=f7cf2444395, createdName=小希言, createdTime=Tue Mar 09 21:01:39 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347533, encodeId=3164134e5332e, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1843613, encodeId=d1fb184361375, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Tue Aug 03 14:04:14 CST 2021, time=2021-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928847, encodeId=e311192884efe, content=<a href='/topic/show?id=80c480961a5' target=_blank style='color:#2F92EE;'>#肌纤维发育不良#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80961, encryptionId=80c480961a5, topicName=肌纤维发育不良)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encryptionId=112222886b8, topicName=临床特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Apr 30 16:04:14 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078054, encodeId=e4be20e8054be, content=<a href='/topic/show?id=8a8580960a5' target=_blank style='color:#2F92EE;'>#肌纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80960, encryptionId=8a8580960a5, topicName=肌纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Wed Sep 08 04:04:14 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927045, encodeId=d5c5192e04535, content=<a href='/topic/show?id=6b57100540e2' target=_blank style='color:#2F92EE;'>#颈动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100540, encryptionId=6b57100540e2, topicName=颈动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6eba113, createdName=xiaoyeshuang, createdTime=Sun May 09 05:04:14 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960517, encodeId=c25e96051eb3, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78415486317, createdName=ms7000001791696491, createdTime=Mon Apr 26 02:19:50 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=946904, encodeId=e7bc94690411, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习到很多新知识, beContent=null, objectType=article, channel=null, level=null, 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GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
    2021-04-26 ms7000001791696491

    0

  8. 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likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210307/b75ef807ee37426488262434e88f2054/ddba9eab8dcf4ab582aa531cff52c0a8.jpg, createdBy=f7cf2444395, createdName=小希言, createdTime=Tue Mar 09 21:01:39 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347533, encodeId=3164134e5332e, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
    2021-03-09 小希言

    #学习#学习到很多新知识

    0

  9. 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likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210307/b75ef807ee37426488262434e88f2054/ddba9eab8dcf4ab582aa531cff52c0a8.jpg, createdBy=f7cf2444395, createdName=小希言, createdTime=Tue Mar 09 21:01:39 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347533, encodeId=3164134e5332e, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]
    2021-03-09 neurowu
  10. 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GetPortalCommentsPageByObjectIdResponse(id=1519614, encodeId=fd17151961437, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Tue Mar 09 08:04:14 CST 2021, time=2021-03-09, status=1, ipAttribution=)]

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