JACC：植入式监护仪可有效预警急性心梗的发生

2019-04-28 不详 MedSci原创

急性冠脉综合征（ACS）很难通过临床症状及时发现，本研究的目的旨在详细描述ALERTS临床试验中的可快速提醒患者ST段异常的植入式心脏监护仪的效果。本研究将907名高危ACS患者随机分成对照组（仪器失活）和实验组，主要终点事件是无系统相关并发症（>90%）。复合主要疗效终点为心脏/不明原因死亡、新发Q波心肌梗死或诊断至治疗间隔时间大于2h。与对照组相比，7天内的疗效终点事件在实验组中并无明显

急性冠脉综合征（ACS）很难通过临床症状及时发现，本研究的目的旨在详细描述ALERTS临床试验中的可快速提醒患者ST段异常的植入式心脏监护仪的效果。

本研究将907名高危ACS患者随机分成对照组（仪器失活）和实验组，主要终点事件是无系统相关并发症（>90%）。复合主要疗效终点为心脏/不明原因死亡、新发Q波心肌梗死或诊断至治疗间隔时间大于2h。与对照组相比，7天内的疗效终点事件在实验组中并无明显降低（[3.8%] vs[4.9%]，p = 0.786），在90天的窗口期内，监护仪可以明显减少诊断至治疗间隔时间（51 min vs. 30.6 h； Pr [pt < pc] >0.999）。在扩展分析后，监护仪组患者的阳性预测值更高，假阳性率更低。

研究结果显示，该心脏预警装置可能有利于高危ACS患者识别无症状事件。

原始出处：

C. Michael et al.Implantable Cardiac Alert System for Early Recognition of ST-Segment Elevation Myocardial Infarction.JACC.2019 Apr.

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2019-07-11 hbwxf

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2020-03-17 villahu

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2019-04-30 chenlianhui

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2019-04-30 docwu2019

#ACC#

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2019-04-30 jiyangfei

#植入#

24 0
[GetPortalCommentsPageByObjectIdResponse(id=1854374, encodeId=cf3618543e457, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jul 11 14:57:00 CST 2019, time=2019-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1748746, encodeId=c0ef1e48746db, content=<a href='/topic/show?id=4087626564c' target=_blank style='color:#2F92EE;'>#植入式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62656, encryptionId=4087626564c, topicName=植入式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cdca36191722, createdName=villahu, createdTime=Tue Mar 17 08:57:00 CST 2020, time=2020-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308382, encodeId=67cc1308382e2, content=<a href='/topic/show?id=8323522e503' target=_blank style='color:#2F92EE;'>#急性心梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52275, encryptionId=8323522e503, topicName=急性心梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Tue Apr 30 01:57:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326195, encodeId=c5281326195ac, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Apr 30 01:57:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520578, encodeId=383c15205e870, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Tue Apr 30 01:57:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551151, encodeId=1c0c155115149, content=<a href='/topic/show?id=e2c1e230796' target=_blank style='color:#2F92EE;'>#监护#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72307, encryptionId=e2c1e230796, topicName=监护)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=477814173963, createdName=bioon6, createdTime=Tue Apr 30 01:57:00 CST 2019, time=2019-04-30, status=1, ipAttribution=)]
2019-04-30 bioon6

#监护#

21 0

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JACC：植入式监护仪可有效预警急性心梗的发生

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