Nanoparticles:糖尿病患者的福音——新型纳米材料可助其伤口愈合

2015-08-12 sunshine 译 MedSci原创

糖尿病患者通常会经受伤口难以愈合的痛苦。而据发表于《纳米粒子》的一项新的研究显示,埃及的科学家已经开发出一种新的载银醋酸纤维素的抗菌纳米材料,可作为新的伤口敷料并促进组织修复。Thanaa Ibrahim Shalaby 及其同事从醋酸纤维素中制备出纳米纤维,材料廉价且容易制造。这种半合成的聚合物可用于胶卷至眼镜涂层的一切东西甚至可用于香烟过滤嘴中。可将这种纳米材料合成纤维,作为促进伤口愈合的安全



糖尿病患者通常会经受伤口难以愈合的痛苦。而据发表于《纳米粒子》的一项新的研究显示,埃及的科学家已经开发出一种新的载银醋酸纤维素的抗菌纳米材料,可作为新的伤口敷料并促进组织修复。

Thanaa Ibrahim Shalaby 及其同事从醋酸纤维素中制备出纳米纤维,材料廉价且容易制造。这种半合成的聚合物可用于胶卷至眼镜涂层的一切东西甚至可用于香烟过滤嘴中。可将这种纳米材料合成纤维,作为促进伤口愈合的安全且可吸收的敷料应用。Shalaby及其同事应用了包括扫描电子显微镜(SEM)及傅立叶变换红外光谱仪(FTIR)在内的各种分析技术对载银纳米粒子的纤维进行表征。

对材料进行表征后,研究人员成功的测试了材料对各种可能导致开放性伤口感染的细菌的抗菌活性。然后研究人员将材料用做糖尿病小鼠皮肤伤口的敷料,并对比有无纳米材料敷料时伤口的愈合速度。敷料不仅可吸收伤口处的渗液,还可以保护伤口免于空气和水分中感染原的污染。伤口愈合过程中,相比于未使用敷料的皮肤伤口,使用敷料还可促进胶原蛋白的合成,有助于恢复正常皮肤所具有的强度和质地等。

原始出处:

Thanaa Ibrahim Shalaby, Nivan Mahmoud Fekry, Amal Sobhy El Sodfy, Amel Gaber El Sheredy and Maisa El Sayed Sayed Ahmed Moustafa,Preparation and characterisation of antibacterial silver-containing nanofibres for wound healing in diabetic mice, International Journal of Nanoparticles, 2015 Vol. 8, No 1

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    2015-08-14 zhaojie88
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