JAMA Surg:社会经济因素对急性阑尾炎发病率的影响

2020-03-09 MedSci原创 MedSci原创

阑尾炎的年龄和性别标准化发病率并非随机分布在不同的地理亚单位中,高收入及受到良好教育群体的急性阑尾炎发病率较低

在针对急性阑尾炎(AA)患者调查发现,穿孔阑尾炎(PA)的发病率与患者社会经济状况(SES)有关。近日研究人员针对这一现象进行了更为系统的研究。

本次研究为针对华盛顿综合医院系统和2010年美国人口普查数据的回顾性研究,考察2008-2012年间,华盛顿州AA和PA的年龄和性别标准化发病率。研究的主要终点为每个普查区(CT)AA和PA的年龄和性别标准化发病率。采用Moran指数(0.0=完全随机发生率;1.0=完全依赖于位置)评估空间自相关性。

在5年的研究期间,全州共有35730名AA患者,包括9780名PA患者,其中16574名为女性(46.4%),中位年龄为29岁。全州AA和PA发病率分别为106/100000和29/100000人-年(PY)。男性人群中发病率较高,在10-19岁达到高峰。年龄和性别标准化的AA发病率表现出显著的正空间自相关(Moran指数,0.30),但PA的自相关仅为AA得到一半(0.16)。AA的中位发病率在热点地区为118.1/100000 PY,而在非热点地区为86.2/100000 PY。非热点地区的社会经济地位高于热点地区:受过大学教育的成年人的平均比例分别为56%和26%,人均收入分别为44691美元和30027美元。

研究发现,阑尾炎的年龄和性别标准化发病率并非随机分布在不同的地理亚单位中,高收入及受到良好教育群体的急性阑尾炎发病率较低。

原始出处:

Reece A. Golz, et al. Geographic Association Between Incidence of Acute Appendicitis and Socioeconomic Status.JAMA Surg. March 4, 2020.

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    2020-03-09 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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