Plos Med:父母患抑郁症对后代青春期认知发展产生重大影响

2021-02-24 MedSci原创 MedSci原创

抑郁症大家都不陌生,但又似乎觉得离自己很远。其实,抑郁症并不是那么少见,据世界卫生组织2017年2月23日发布的一份关于抑郁症的全球统计报告显示,全球约有3.22亿人患抑郁症,占全球人口的4.4%,也

抑郁症大家都不陌生,但又似乎觉得离自己很远。其实,抑郁症并不是那么少见,据世界卫生组织2017223日发布的一份关于抑郁症的全球统计报告显示,全球约有3.22亿人患抑郁症,占全球人口的4.4%,也就是平均每23个人里就有一名抑郁症患者.抑郁症患者不仅对自身,还对家庭成员产生不利影响,特别是对后代。已有研究显示,围产期父母抑郁与儿童早期认知能力之间的负相关。然而,到目前为止,父母患抑郁对后代青春期认知发展的影响知之甚少。

近日,发表在Plos Med杂志的一项研究显示,父母患抑郁症对后代青春期认知发展产生负面影响。同时,强调了父母患抑郁症与认知发展之间代际关系,这种关联贯穿于早期生命过程到青春期。

在这项研究中,研究人员对2012年中国具有全国代表性的228110-15岁的青少年进行调查,探讨了父母抑郁状态与后代青春期认知表现(如数学、词汇和工作记忆)的关系。

结果先显示,父母患抑郁长达6年后,在一系列认知表现测试中的后代认知表现更差有关。即使调整了混杂变量(如性别、父母的教育水平等)以及后代在幼儿期的认知表现等,这些关联仍然显著存在。另外,与年龄较大的青少年(即12-15岁)相比,父母患抑郁症与年龄较小的青少年(即10-11岁)的认知表现有更强的关联性。研究进一步发现,产妇抑郁症的严重程度越高,后代青春期的认知表现越差,存在剂量-反应关系。

综上,大多数研究父母抑郁症对后代认知结果的影响的研究都局限于幼儿期,特别是重点显示了母亲抑郁症对早期认知发展产生负面影响。该研究不仅证实了父母抑郁症与子代青春期认知发展的影响,而且还可通过提前预防和治疗父母抑郁而对后代儿童期和青春期认知发展进行干预。

原始出处

Zhihui Li, et al,Associations of parental depression during adolescence with cognitive development in later life in China: A population-based cohort study.Plos Med.2021.https://doi.org/10.1371/journal.pmed.1003464

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    2021-05-24 ooo0830

    抑郁症

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    2021-03-06 474576351

    优秀,不错

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