2021年10月16日简报:张文宏认为新冠疫苗接种目标是预防和降低重症;未来几周,更多新冠治疗药物将批量问世;多国选择“与新冠共存”政策;全球共有超过50个国家和地区确认接种科兴疫苗的旅行者可入境,71个国家接受国药疫苗接种者入境

2021-10-16 MedSci整理 MedSci整理

截至北京时间2021年10月16日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎(COVID-19)病例超过2亿4078万例,新增405,102例,达到240,788,

截至北京时间2021年10月16日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎COVID-19)病例超过2亿4078万例,新增421,804例,达到240,788,741例。累计死亡病例490.3万例,达到4,903,886例。新增死亡为6,753例。康复为218,023,919例,重症和危重症病人达到79,801例;全球新冠确诊病例超过100万例的国家达35个,110个国家病例超10万例。昨日报道:2021年10月15日简报:若2022年初疫苗接种率能超过85%,中国或有望打开国门;非洲超85%新冠患者未被发现;葡萄牙12岁以上的人中有 98% 接种了疫苗

梅斯医学注意到,全球重症人数再次回落到8万例以内。死亡已降至一年来最低水平,再过2周,每日死亡病例将降至3000例以内,即达到疫情全球暴发以来的最低值(即从2020年4月至今),疫情将真正进行拐点。以前担忧的冬季可能新冠更为严重,但是,从一年多来看,新冠并无明显的季节特征,因此,冬季新冠将更为严重的说法还不能得到验证。

目前疫苗接种的目标不再是预防感染,而是预防重症和死亡,这对于全球所有的疫苗而言,都是能办得到的。新冠病毒大概率无法从地球上消灭,未来会进化为常驻病毒,人类必需学会与新冠共存。一方面通过疫苗加强免疫,另一方面新冠病毒不断进化,毒力降低,再次新冠治疗药物不断被开发出来,三重力量结合,人类将能实现与病毒的共存。

当然,我们也注意到,在全球各国,仍然有部分人群不愿意接种疫苗,这对于开放国门而言,这部分人群便处于高风险之中。从以色列来看,少数未接种疫苗的人群成为重症和死亡的主要人群。因此,疫苗的普及程度就变得十分重要。

张文宏表示疫苗接种目标已经转变,把疾病的危害性降到最低水平

国家传染病医学中心主任、复旦大学附属华山医院感染科主任张文宏教授周二在上海生物医药产业周浦江医药健康产融创新发展峰会上,谈到新冠疫苗接种时表示:“今天疫苗接种的目标定位已经发生了转变。我们现在没有办法通过疫苗接种完全阻挡疾病的传播,疫苗接种之后的目标主要是把疾病的危害性降到最低的水平。”

张文宏表示,即便是在国际上进行第三针疫苗的接种延长和提高疫苗的保护效力,我们主要目标也仍然是预防和降低重症。

张文宏援引截至今年8月29日发表的美国数据称,疫苗接种后的突破性感染比例已经上升至36%左右。“这说明较多的人打过疫苗还是被感染了,随着时间的推移,所有打过两针的人出现感染会越来越常见。”张文宏说道,“我们看到新加坡民众的两针疫苗接种率已经达到80%以上,但仍然没有看到疫情被终止的迹象,反而发现新加坡在逐步放开后出现发病率进一步上升。”

他再次强调接种疫苗的必要性。“虽然新冠病毒变异使得发病率上升了,但是由于接种了疫苗,一些国家的病死率已经下降到相当低的水平,部分国家逐渐会选择带疫开放。”张文宏表示,“未来的趋势是群体免疫的水平会逐渐升高,人们要么通过疫苗接种疫苗获得免疫,要么通过感染获得免疫。”

多国选择“与新冠共存”政策

众所周知,新西兰此前抗疫“成绩单”一直算是国际层面的“优等生”,其此前一直坚持确诊病例清零政策。但由于“德尔塔”变异毒株的出现,让新西兰这个优等生也慢慢堕落,选择“躺平”,宣布采取“与新冠共存”的政策。

如今,这股“躺平”热潮,慢慢刮到了亚洲地区。除了已经宣布“与新冠共存”的韩国外,近日,刚刚上任的日本首相岸田文雄也表示要紧随其后,打造一个“与新冠共存”的日本社会。

虽然有些国家口头上不说,但其所作所为已经在往“与新冠共存”政策靠拢,比如美国、巴西、印度。值得一提的是,中国作为全球人口最多的国家,是此次新冠疫情中的“奇迹”。为了保障中国人民的生命安全,中国始终坚持采用科学有效的防疫手段,控制疫情发展,采取确诊病例清零政策。

未来几周,更多新冠治疗药物将批量问世

新冠口服药正在加速问世。本月早些时候,默沙东(Merck)宣布其试验性新冠口服药Molnupiravir可将新冠病例住院或死亡风险降低约50%。

十天后(10月11日),英国阿斯利康公布其新冠抗体鸡尾酒药物(AZD7442)III期临床试验结果:注射600毫克剂量的该药物可降低50%的重症和死亡风险。

四季度全球4款主要的新冠口服药将逐一披露3期临床数据,包括中国开拓药业研发的AR拮抗剂普克鲁胺(GT0918)、默沙东RNA聚合酶抑制剂Molnupiravir、罗氏RNA聚合酶抑制剂AT-527和辉瑞3CL蛋白酶抑制剂PF-07321332,如果取得积极结果,进展快的产品有望于2021年底前在欧、美及南美等地获得紧急使用授权(EUA)上市。

罗氏、辉瑞、盐野义和其他研发新冠口服药的公司将在2021Q4和2022Q1期间公布更多的药物试验数据。

美国将从11月8日起允许完全接种新冠疫苗的外国旅客入境

美国白宫15日说,美国将从11月8日起允许完全接种新冠疫苗的外国旅客乘坐国际航班或通过水陆口岸入境。

白宫助理新闻秘书凯文·穆尼奥斯当天在社交媒体上发文说,美国政府有关国际旅行的最新规定将于11月8日开始实施,适用于乘坐国际航班或通过水陆口岸入境的旅客。

据美国媒体报道,白宫将于11月8日前公布符合入境接种要求的新冠疫苗种类、未完全接种新冠疫苗者可入境美国的“极少数例外情况”以及其他细节。

报道援引一名未透露姓名官员的话说,美疾病控制和预防中心此前已通知各航空公司,入境美国的航空旅客可接种的新冠疫苗包括美食品和药物管理局批准和授权的疫苗、获得世界卫生组织紧急使用认证的疫苗。预计上述标准也将适用于通过水陆口岸入境美国的外国旅客。

美国旅游协会当天发表声明对此表示欢迎,认为此举对美国旅游业的持续复苏“至关重要”。

白宫9月20日曾宣布,美国政府将于11月初允许完全接种新冠疫苗的外国旅客乘坐国际航班入境,但入境时须出示完全接种疫苗的证明,以及出发前72小时内新冠检测阴性证明。10月12日,美国土安全部宣布,将从11月起允许完全接种新冠疫苗的旅客从加拿大和墨西哥通过水陆口岸入境美国进行探亲、访友或旅游等“非必要活动”,但入境时须出示完全接种疫苗的证明。

11月1日起,完成疫苗接种的国际旅客入境悉尼无须隔离

澳大利亚新南威尔士州州长佩罗特日前宣布,悉尼将从11月1日起允许完成新冠疫苗接种的国际旅客入境,并且无需隔离。

据报道,为遏制冠病大流行,澳洲自去年3月起关闭国际边境,只有澳洲公民或永久居民获准入境,而他们在入境之后必须自费在酒店自我隔离两个星期,费用可达数千澳元。

佩罗特表示,从 11 月 1 日起,接种疫苗的旅客必须在登机前检测呈阴性,但在抵达时根本不需要隔离。他说:“我们希望人们回来,我们要带领国家走出这场大流行病……我们将向全世界开放悉尼和新南威尔士州。”

韩国总统文在寅夫妇补打新冠疫苗

当地时间15日上午,韩国总统文在寅和夫人金正淑前往首尔市的国立中央医疗院,补打新冠疫苗。

报道称,文在寅分别于3月23日和4月30日各打1针阿斯利康疫苗,但第3针接种辉瑞疫苗。目前,韩国施打加强针只用辉瑞疫苗,且只在预防接种中心和委托医疗机构补打疫苗。

报道称,韩国政府正在为打第2针已过半年的高龄人群和医务人员等进行第3针接种。有出境等特殊情况者,全程接种不到6个月也可补打疫苗。

虽然到目前为止,接种还不满六个月,不过一方面由于文在寅月底有出访行程,为了起保护作用,同时也为了鼓励民众接种新冠疫苗第三剂,所以文在寅夫妇才决定带头接种。青瓦台称,此举还有鼓励民众打加强针的考虑。

斐济双剂新冠疫苗接种率超80% 将于11月开放边境

据澳大利亚广播公司报道,斐济将从11月11日起对部分国际游客重新开放。自6月以来,斐济因为高疫苗接种率扭转了新冠疫情的影响。斐济总理姆拜尼马拉马称,斐济在管理免隔离旅行方面“完全有信心”。

在持续封锁数月后,身处悉尼的丽莎思韦特表示,能预订到斐济的家庭旅行让她觉得非常兴奋。一些准备去热带地区度假的澳大利亚家庭表示,到斐济度假比在澳大利亚各州间旅行更放心,因为斐济的双剂新冠疫苗接种率已超过80%。

斐济政府除了推出“不接种不工作”的政策外,还通过开设价值5.1万斐济元(约合3.3万澳元)的“疫苗彩票”的活动来鼓励公民接种。自2021年6月以来,斐济从世界最高的人均新冠感染率转变至已有 80% 以上的人完成全部两剂疫苗接种。

姆拜尼马拉马表示,斐济将从11月11日起向包括澳大利亚、美国和新西兰在内的部分国家重新开放边境。斐济航空的首趟旅游航班定于12月1日起飞,澳大利亚航空公司和维珍澳大利亚航空也将于12月晚些时候恢复旅游航班。

全球疫苗接种后旅行状况

随着全球各国疫苗接种率的提高,疫苗互认已成为未来一个很重要的工作。在疫情爆发将近两年之际,中国疫苗正获得世界范围内的认可。10月3日,根据监控全球各地对不同新冠疫苗接种政策的网站Visaguide.world的不完全统计,全球共有超过50个国家和地区确认接种科兴疫苗的旅行者可入境,71个国家接受国药疫苗接种者入境,10个国家承认接种中国康希诺疫苗的旅行者为有效接种,同时认可辉瑞、莫德纳、卫星5和印版阿斯利康的,分别有124个、87个、73和63个国际和地区。尽管这个数据与批准疫苗紧急使用的国家和地区数量并不相等。但这个网站仍然提供了一个国人旅行的疫苗承认名单与指南。

据这家网站公布的相关信息,西班牙是首批决定接受国药疫苗作为有效豁免证明的欧盟国家之一。但已脱欧的英国,则没有承认这款疫苗。匈牙利与塞尔维亚是巴尔干半岛国家批准国药疫苗较早的国家。他们早已向国人敞开了大门。

据相关信息表明,预估年底前欧盟也将宣布接种国产疫苗入境政策,并将采取与美国一致的以世卫批准的疫苗名单给予承认。

CureVac 宣布放弃新冠 mRNA 疫苗研发,后续开发重心转移到第二代疫苗

10 月 12 日,CureVac 宣布从 EMA 批准程序中撤出其第一代 COVID-19 候选疫苗 CVnCoV,这一决定也意味着该公司与欧盟委员会此前达成的 4.05 亿剂疫苗预采购协议将终止。

根据 CureVac 官方公告,第一代 COVID-19mRNA 疫苗 CVnCoV 预计最早在 2022 年 Q2 才能获批。鉴于当前疫情形势的发展变化,CureVac 认为有效应对病毒和新出现的变种的要求已经改变,将后续开发重心转移到与葛兰素史克合作的第二代疫苗上更有助于解决公共卫生需求。

该公司期望在 2022 年上半年将二代 mRNA 疫苗推进到后期临床,并在同年争取监管部门批准。

而在 9 月 28 日,法国制药巨头赛诺菲宣布,停止信使核糖核酸新冠疫苗的三期实验,原因在于该款疫苗已经错过投放市场的最佳时机,该公司表示将继续推进重组蛋白新冠疫苗的研发工作。

全球主要国家新冠死亡率都降至每百万人5人以内

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
    2022-04-07 mhm289
  3. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
    2021-10-17 bioon3
  5. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
    2021-10-16 ms5000001429938748

    谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1921852, encodeId=72381921852b4, content=<a href='/topic/show?id=4f0a6469837' target=_blank style='color:#2F92EE;'>#治疗药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64698, encryptionId=4f0a6469837, topicName=治疗药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9d3459, createdName=周虎, createdTime=Sat Sep 10 09:35:43 CST 2022, time=2022-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998512, encodeId=ca1b1998512e0, content=<a href='/topic/show?id=20a95669854' target=_blank style='color:#2F92EE;'>#接种者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56698, encryptionId=20a95669854, topicName=接种者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af60254, createdName=mhm289, createdTime=Thu Apr 07 00:35:43 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1258107, encodeId=2942125810ef9, content=<a href='/topic/show?id=f538e0501e9' target=_blank style='color:#2F92EE;'>#疫苗接种#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70501, encryptionId=f538e0501e9, topicName=疫苗接种)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260514, encodeId=c1f2126051456, content=<a href='/topic/show?id=1ed65e476b8' target=_blank style='color:#2F92EE;'>#政策#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57476, encryptionId=1ed65e476b8, topicName=政策)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sun Oct 17 22:35:43 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061101, encodeId=8b4c1061101f3, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6ec5508419, createdName=ms5000001429938748, createdTime=Sat Oct 16 21:06:07 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061029, encodeId=67bc10610294f, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=348, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sat Oct 16 14:03:26 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060945, encodeId=83af106094599, content=这项全国性队列研究使用了法国国家健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sat Oct 16 08:55:42 CST 2021, time=2021-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1060915, encodeId=acf1106091518, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=644b2182796, createdName=1207866fm50(暂无昵称), createdTime=Sat Oct 16 07:59:12 CST 2021, time=2021-10-16, status=1, ipAttribution=)]
    2021-10-16 病毒猎手

    #新冠病毒#估计国内应该是明年后,会全面开放,或有条件有序开放。例如可以选择北京,上海,广州几个主要口岸城市进行先开放,因为这些城市#新冠疫苗#接种程度高,医疗救治水平也高,如果问题不大,再逐步开放内地,最终实现全面开放的可能。

    0

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    2021-10-16 查查佳佳

    这项全国性队列研究使用了法国国家健康

    0

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    2021-10-16 1207866fm50(暂无昵称)

    谢谢分享

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