Eur Radiol:CTA对前列腺动脉栓塞术的价值

2021-04-17 shaosai MedSci原创

前列腺动脉栓塞术是一个技术上相对困难的手术。然而到目前为止,对影响PAE技术困难度因素的研究十分有限,且迄今为止大多数的相关研究均对患者变量使用主观测量。

    前列腺动脉栓塞术(PAE)是一个技术上相对困难的手术。然而到目前为止,对影响PAE技术困难度因素的研究十分有限,且迄今为止大多数的相关研究均对患者变量使用主观测量而不是客观测量进行研究和评价。已有学者指出,髂内动脉粥样硬化和先天的髂血管弯曲与技术困难度增加有关,同时髂内动脉粥样硬化的主观分级与患者接受的辐射剂量有关。因此,不同的患者在术中所接受的辐射剂量、技术困难度以及所需时间均存在差异。

 

    近日,发表在European Radiology杂志的一项研究通过术前计算机断层摄影血管造影(CTA)的客观(而非主观)测量评价何种患者因素将增加PAE手术的困难度,并探讨了这些因素在预测技术困难度以及手术相关的辐射剂量的有用性,为临床术前预测手术效果及方案制定提供了影像学支持。

    本研究回顾性的纳入了连续的75例接受PAE治疗的患者的资料。从计划的计算机断层血管造影(CTA)中确定和客观测量多个患者的预测变量。术中导航的血管角度、前列腺体积、前列腺动脉(PA)直径、PA起源、主动脉粥样硬化、髂血管弯曲度和基线人口统计学数据与结果变量(透视时间,空气比释动能(AK),剂量区域产品(DAP))相关,锥体束CTs (CBCTs))的数量以及是否双侧栓塞是可能的(技术上成功)。资料分析采用线性回归、方差分析、t检验及卡方检验。

    主动脉粥样硬化严重程度显著增加了透视时间(p = 0.004),而前列腺动脉较小(p = 0.009)和术前前列腺容积较小(p = 0.038)的患者AK显著增加。血管弯曲和前列腺动脉起源的增加对透视时间或DAP没有显著影响。前列腺动脉较小(p = 0.007)也会增加单侧栓塞或技术失败的可能性。

表1 预测变量与结果变量之间的简单线性回归分析结果。回归系数(β)和p值在每个框中显示,统计显著值用斜体表示。

图1 动脉粥样硬化严重程度与透视时间的关系。

表2 对双侧栓塞成功患者和非双侧栓塞患者(单侧栓塞或技术失败)的基线人口统计学数据和预测变量进行比较。

    本研究结果表明,动脉粥样硬化严重程度的增加和前列腺小动脉的存在分别增加了透视时间和AK,术前前列腺容积较小也会增加手术过程中的AK,前列腺动脉较细也增加了单侧栓塞或技术失败的可能性。

    在术前CT血管造影提示有小腺体(< 40ml)、明显的动脉粥样硬化和小前列腺动脉(< 1.5 mm)的患者手术困难度将增加,这提示临床医生这类患者所需手术时间较长且风险较高,将进一步指导临床对手术的准备及患者的管理

原始出处:

Luke Lintin,Thomas Barge,Phil Boardman,et al. Predictors of technical outcome for prostatic artery embolisation using pre-procedural CT angiography.DOI:10.1007/s00330-020-07244-3

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    2022-01-16 windight
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    2021-06-16 ms8000001709311190

    好文章分享

    0

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    2021-04-22 科研科研科研

    CTA对前列腺动脉栓塞术的价值

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    2021-04-17 jyzxjiangqin

    好文章!

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