Stroke:年龄较小和抑郁症状预测脑卒中/TIA后广泛性焦虑的高风险

2019-08-13 xing.T MedSci原创

由此可见,卒中/TIA后焦虑很常见,并且与卒中后抑郁症状和年龄密切相关,即使在没有严重抑郁症状的个体中也是如此。鉴于年轻幸存者中广泛性焦虑和抑郁症状的发生频率较高,因此需要常规筛查抑郁症并进一步评估卒中/TIA患者的焦虑情绪。

卒中/短暂性脑缺血发作(TIA)后抑郁和焦虑很常见。这些疾病与不良功能结局和较差的生活质量有关。然而,很少有研究探讨卒中后广泛性焦虑风险的预测因素,特别是对于没有合并抑郁症状的患者。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员的目的是探索卒中/TIA后广泛性焦虑高风险的预测因子。

在2年期间(2012年4月至2014年4月)连续就诊卒中和TIA患者被纳入研究,这些患者讲英语,并非严重失语,并同意完成神经心理检查。广泛性焦虑和抑郁症状分别使用广义焦虑障碍7项量表和流行病学研究中心抑郁量表进行评估。

258名患者完成了广泛性焦虑症7项量表,其中56名(22%)参与者患有广泛性焦虑症(分数≥10)。年龄较小(比值比=0.96; 95%CI为0.93-0.99; P=0.004)和更重的抑郁症状(比值比=1.20; 95CI为1.14-1.26;P≤0.001)是卒中/TIA后患者发生广泛性焦虑高风险的重要预测因素。与年长患者相比,年轻患者(≤50岁)患抑郁症和广泛性焦虑的风险显著更高(30% vs. 12%,χ2[1,N=258]=10.98,P=0.001)。该研究的模型解释了卒中后广泛性焦虑风险56%的变异。在没有严重抑郁症状的患者中(n=193,75%),年龄和抑郁症状的严重程度仍然是与广泛性焦虑风险相关的因素。

由此可见,卒中/TIA后焦虑很常见,并且与卒中后抑郁症状和年龄密切相关,即使在没有严重抑郁症状的个体中也是如此。鉴于年轻幸存者中广泛性焦虑和抑郁症状的发生频率较高,因此需要常规筛查抑郁症并进一步评估卒中/TIA患者的焦虑情绪。 
 
原始出处:
 
Arunima Kapoor.et al.Younger Age and Depressive Symptoms Predict High Risk of Generalized Anxiety After Stroke and Transient Ischemic Attack.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025464
 
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  2. [GetPortalCommentsPageByObjectIdResponse(id=1862102, encodeId=d58f18621020e, content=<a href='/topic/show?id=a374102813a1' target=_blank style='color:#2F92EE;'>#高风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102813, encryptionId=a374102813a1, topicName=高风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Tue Oct 08 10:17:00 CST 2019, time=2019-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434892, encodeId=16ad1434892c4, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 15 11:17:00 CST 2019, time=2019-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026430, encodeId=9a401026430f2, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Aug 13 23:17:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050504, encodeId=49b71050504ec, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Tue Aug 13 23:17:00 CST 2019, time=2019-08-13, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1862102, encodeId=d58f18621020e, content=<a href='/topic/show?id=a374102813a1' target=_blank style='color:#2F92EE;'>#高风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102813, encryptionId=a374102813a1, topicName=高风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Tue Oct 08 10:17:00 CST 2019, time=2019-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434892, encodeId=16ad1434892c4, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 15 11:17:00 CST 2019, time=2019-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026430, encodeId=9a401026430f2, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Aug 13 23:17:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050504, encodeId=49b71050504ec, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Tue Aug 13 23:17:00 CST 2019, time=2019-08-13, status=1, ipAttribution=)]
    2019-08-13 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2019-08-13 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

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