JAMA Neurol:脑MRI-DWI阳性与轻微TIA人群中风复发风险

2019-09-25 MedSci MedSci原创

本研究提示,传统上被认为是低风险的短暂性脑缺血发作和症状的患者,在脑部MRI扫描中具有弥散限制(DWI阳性)人群的急性中风实质性风险增加

早期短暂性脑缺血发作(TIA) 治疗可降低中风风险,有运动、言语或长时间症状的患者患中风复发的风险最高,需接受全面检查。近日研究人员通过弥散加权成像(DWI)磁共振成像(MRI)扫描对高风险人群进行识别。

DOUBT研究中,1028例低风险、短暂或轻微症状TIA患者在发病后8天内接受脑部MRI检查,并进行详细的神经学评估。

1028名患者,其中522名女性和506名男性;平均年龄,63.0岁。共139例(13.5%)急性脑卒中患者在MRI检查中发现弥散限制(DWI阳性)。在进行脑MRI后,308例患者(30.0%)的最终诊断被修订。1年中有7例(0.7%)复发性卒中。1年时,DWI-阳性脑MRI扫描与复发性卒中(RR:6.4)的风险增加相关。脑部MRI扫描不存在DWI-阳性病变,对复发性卒中具有99.8%的阴性预测值。与多变量建模中的卒中MRI证据相关的因素是老年(OR:1.02),男性(OR:2.03),运动或言语症状(OR:2.12),持续症状(OR:1.97),无既往相同症状事件(OR:1.87)和初始神经系统检查的异常结果(OR:1.71)。

本研究提示,传统上被认为是低风险的短暂性脑缺血发作和症状的患者,在脑部MRI扫描中具有弥散限制(DWI阳性)人群的急性中风实质性风险增加。

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    2019-12-06 yinhl1978
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    2019-09-27 hyf028
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    2019-09-25 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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