J Clin Endocrinol Metab:增加膳食钙摄入量预防骨质疏松,可能并不靠谱

2019-10-11 国际糖尿病编辑部 国际糖尿病

众所周知,现实生活中人们的钙摄入量通常低于推荐水平,故临床医生常推荐增加钙摄入量以促进骨骼健康。绝经后女性无疑是一个需要增加钙摄入量来促进骨骼健康的重点人群。那么,对于绝经后女性而言,膳食钙摄入量到底会对骨量流失速率有着怎样的影响?通过增加膳食钙摄入量来预防骨质疏松是否可行?近期发表的一项最新研究专门探讨了老年女性膳食钙摄入量与骨量流失速率之间的关系,其研究结果发表在近期的J Clin Endoc

众所周知,现实生活中人们的钙摄入量通常低于推荐水平,故临床医生常推荐增加钙摄入量以促进骨骼健康。绝经后女性无疑是一个需要增加钙摄入量来促进骨骼健康的重点人群。那么,对于绝经后女性而言,膳食钙摄入量到底会对骨量流失速率有着怎样的影响?通过增加膳食钙摄入量来预防骨质疏松是否可行?近期发表的一项最新研究专门探讨了老年女性膳食钙摄入量与骨量流失速率之间的关系,其研究结果发表在近期的J Clin Endocrinol Metab 上。

该研究专门探讨了老年女性膳食钙摄入量与骨量流失速率之间的关系。研究对一项随机对照试验中年龄大于65岁、未接受骨质疏松症治疗、未应用钙补充剂、基线时评估了钙摄入量及骨密度(BMD)的1994例骨质疏松症女性的观察性数据进行了分析。其中,安慰剂组女性受试者为698例。随访6年间,共计对脊柱、全髋、股骨颈及全身总骨密度(BMD)进行了三次评估。

研究结果发现,受试患者的平均钙摄入量为886 mg/d。不论是否校正基线年龄、身高、体重、体力活动、饮酒量、吸烟状况、既往激素替代治疗情况,基线各部位的BMD与钙摄入量的五分位距分组并无相关性。不论是否校正协变量,各部位骨量丢失与钙摄入量五分位距分组之间均无相关性。此外,全身骨平衡(即骨矿物质含量的变化)也与个人钙摄入量无关(P=0.99)。

上述结果表明,绝经后骨量流失与膳食钙摄入量无关。因此,增加膳食钙输入量的策略可能难以对绝经后女性骨质疏松症的患病率及发病率产生现实影响。

原始出处:
Sarah M Bristow, Anne M Horne, Greg D Gamble, et al. Dietary Calcium Intake and Bone Loss Over 6 Years in Osteopenic Postmenopausal Women. The Journal of Clinical Endocrinology & Metabolism.  21 March 2019.

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    2019-12-27 guojianrong
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    2020-03-27 一闲
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    2020-03-13 lmm397
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    2019-10-13 heli0118
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    2019-10-13 Eleven17
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    2019-10-13 yjs木玉

    好好好好好好

    0

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    2019-10-12 飛歌

    学习了很有用不错

    0

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