Janssen的Imbruvica最终被纳入NHS

2018-02-01 MedSci MedSci原创

Janssen的Imbruvica将被纳入NHS,用于某些患有套细胞淋巴瘤(MCL)患者的常规治疗,此前成本监管机构已经为该药发布了最后的绿灯。在最后的指导方针中,英国国家医疗服务体系批准Imbruvica(ibrutinib)用于治疗只有这一种选择的患者。该机构之前表示,它不能为整个MCL患者群推荐该药,因为它没有提供NHS的资金价值,但是在二级保健中,Imbruvica可以被认为处于"临终"阈


Janssen的Imbruvica将被纳入NHS,用于某些患有套细胞淋巴瘤(MCL)患者的常规治疗,此前成本监管机构已经为该药发布了最后的绿灯。

在最后的指导方针中,英国国家医疗服务体系批准Imbruvica(ibrutinib)用于治疗只有这一种选择的患者。

该机构之前表示,它不能为整个MCL患者群推荐该药,因为它没有提供NHS的资金价值,但是在二级保健中,Imbruvica可以被认为处于"临终"阈值之内。其成本效益可能低于每QALY上涨49,848英镑。

该批准还取决于与NHS英格兰商业准入协议中商定的保密折扣继续提供该药物。
Imbruvica是第一个布鲁顿酪氨酸激酶(BTK)抑制剂,用于特异性阻断BTK蛋白引起恶性B细胞繁殖和扩散。


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    2018-03-16 执着追梦

    学习.谢谢分享

    0

  2. 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    2018-03-10 执着追梦

    学习.谢谢分享

    0

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    2018-03-09 执着追梦

    学习.谢谢分享

    0

  4. 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createdTime=Sat Mar 10 06:11:20 CST 2018, time=2018-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294419, encodeId=87fe294419d1, content=学习.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Fri Mar 09 06:58:05 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289541, encodeId=48e72895418a, content=学习.学习付出, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Wed Feb 21 00:44:44 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1312495, encodeId=9537131249596, content=<a href='/topic/show?id=dc0c9e5231' target=_blank style='color:#2F92EE;'>#Imbruvica#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9752, encryptionId=dc0c9e5231, topicName=Imbruvica)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b27406, createdName=syscxl, createdTime=Sat Feb 03 13:23:00 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515260, encodeId=7b9e151526056, content=<a href='/topic/show?id=402a12e83da' target=_blank style='color:#2F92EE;'>#NHS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12783, encryptionId=402a12e83da, topicName=NHS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=626110750337, createdName=小几洁, createdTime=Sat Feb 03 13:23:00 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527085, encodeId=f256152e085ac, content=<a href='/topic/show?id=ad4410248b5' target=_blank style='color:#2F92EE;'>#Janssen#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10248, encryptionId=ad4410248b5, topicName=Janssen)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c0ca11798386, createdName=zhang92564, createdTime=Sat Feb 03 13:23:00 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284699, encodeId=9e1f2846991f, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Feb 03 08:07:36 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284395, encodeId=e877284395ed, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:26:03 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-21 执着追梦

    学习.学习付出

    0

  5. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-03 syscxl
  6. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-03 小几洁
  7. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
  8. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-03 大爰

    学习了谢谢分享!!

    0

  9. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-02 榄枷檬

    谢谢分享

    0

  10. 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2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284394, encodeId=f866284394d4, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Feb 02 07:25:57 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-02 榄枷檬

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