PLoS One:视网膜病变是否可以预测2型糖尿病患者的卒中复发增加?

2019-01-22 MedSci MedSci原创

瑞典哥德堡大学Sahlgrenska学院医学研究所分子与临床医学系的Hjelmgren O等人近日在PLoS One杂志上发表一项重要的工作,他们研究了视网膜病变是否会增加2型糖尿病患者卒中复发的风险。此外,他们还与非糖尿病患者进行比较,研究2型糖尿病卒中患者卒中复发的风险是否增加;如果患有2型糖尿病的卒中患者,无论视网膜病变是否发生,颈动脉狭窄的发生率是否更高。

瑞典哥德堡大学Sahlgrenska学院医学研究所分子与临床医学系的Hjelmgren O等人近日在PLoS One杂志上发表一项重要的工作,他们研究了视网膜病变是否会增加2型糖尿病患者卒中复发的风险。此外,他们还与非糖尿病患者进行比较,研究2型糖尿病卒中患者卒中复发的风险是否增加;如果患有2型糖尿病的卒中患者,无论视网膜病变是否发生,颈动脉狭窄的发生率是否更高。

他们纳入了445名患有2型糖尿病的患者和与之匹配的445名无糖尿病患者作为对照组,他们都患有一次中风的经历。从登记和医疗记录中获得有关视网膜病变、危险因素和卒中复发等信息。

结果发现,视网膜病变并未增加糖尿病患者卒中复发的风险,HR 为0.89(0.51-1.53),p = 0.67。与非糖尿病相比,糖尿病患者的中风复发风险并未增加。与非糖尿病患者相比,糖尿病患者颈动脉狭窄的患病率增加,为1.69(1.15-2.48),p = 0.008。与没有视网膜病变的糖尿病患者相比,患有视网膜病变的糖尿病患者颈动脉狭窄的患病率没有增加。

因此,他们认为,视网膜病变不是2型糖尿病患者中风复发或颈动脉狭窄的预测因素。

FINnish糖尿病危险评分问卷

原文出处:

Hjelmgren, O., et al., Does retinopathy predict stroke recurrence in type 2 diabetes patients: A retrospective study? PLoS One, 2019. 14(1): p. e0210832.

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    2019-01-24 zutt
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    2019-01-23 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1790321, encodeId=af2a1e903216a, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Aug 07 01:30:00 CST 2019, time=2019-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1270165, encodeId=03e412e016571, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Thu Jan 24 12:30:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383525, encodeId=9e1b1383525ad, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Thu Jan 24 12:30:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391622, encodeId=d22713916229f, content=<a href='/topic/show?id=f8ab3603664' target=_blank style='color:#2F92EE;'>#卒中复发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36036, encryptionId=f8ab3603664, topicName=卒中复发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Thu Jan 24 12:30:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413975, encodeId=a09114139e5c3, content=<a href='/topic/show?id=27b290e82f4' target=_blank style='color:#2F92EE;'>#视网膜病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90782, encryptionId=27b290e82f4, topicName=视网膜病变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7143034078, createdName=zhanfl, createdTime=Thu Jan 24 12:30:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474692, encodeId=198214e4692e0, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Thu Jan 24 12:30:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026272, encodeId=615110262e2b0, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Wed Jan 23 00:30:00 CST 2019, time=2019-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042212, encodeId=942f1042212d9, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Jan 23 00:30:00 CST 2019, time=2019-01-23, status=1, ipAttribution=)]
    2019-01-23 misszhang

    谢谢MedSci提供最新的资讯

    0

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