J Hypertens:空腹血糖升高是高血压危险因素

2018-08-19 xing.T MedSci原创

由此可见,空腹血糖升高是高血压发病的独立危险因素。需要进一步的研究来确定降糖治疗是否可以预防高血压的发生。

近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在通过大规模纵向研究来明确较高的空腹血糖水平是否可预测高血压

研究人员使用了2004年接受年度体检的13201名日本人的数据进行了一项为期5年的回顾性队列研究,并在5年后进行了重新评估。该研究纳入了2004年年龄为30-85岁且没有糖尿病或高血压的个体。研究人员计算空腹血糖水平每增加10mg/dl后高血压的5年累积发生率。此外,研究人员通过Logistic回归分析评估了调整年龄、性别、BMI、吸烟和饮酒习惯、血脂异常、慢性肾病、血清尿酸和空腹血糖水平后发生高血压的危险因素和比值比(OR)。

研究人员分析了2004年没有糖尿病或高血压的10157名参与者(年龄:48.9±10.7岁; 43.4%为男性)。经过多重调整后,较高的基线血糖水平是高血压的独立危险因素(OR为1.176; 95%CI为1.086-1.275),衰老、女性、更大的BMI、饮酒和更高的血清尿酸也是如此。按性别分层后,较高的基线血糖水平是女性(OR为1.295; 95%CI为1.135-1.478)和男性(OR为1.108; 95%CI为1.001-1.227)高血压患者的独立危险因素。当研究人员使用糖化血红蛋白而不是血糖进行相同的分析时,发现糖化血红蛋白不是高血压的危险因素。

由此可见,空腹血糖升高是高血压发病的独立危险因素。需要进一步的研究来确定降糖治疗是否可以预防高血压的发生。

原始出处:

Kuwabara, Masanari,et al. Fasting blood glucose is predictive of hypertension in a general Japanese population.Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Fasting_blood_glucose_is_predictive_of.97354.aspx

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    2018-08-27 huangshang9812

    哈哈哈,学习了

    0

  5. 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  6. 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    2018-08-21 smartxiuxiu

    赞成

    0

  7. 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    2018-08-20 惠映实验室

    学习了,谢谢分享。

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Mon Aug 20 07:06:59 CST 2018, time=2018-08-20, status=1, ipAttribution=)]
    2018-08-20 明月清辉

    谢谢分享,学习了

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Mon Aug 20 07:06:59 CST 2018, time=2018-08-20, status=1, ipAttribution=)]
    2018-08-20 phoebeyan520

    学习了

    0

  10. 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    2018-08-20 183****7028

    学习

    0

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