Lancet:首例“仿生重建术”传喜讯

2015-03-02 孟秋君 编译 医学论坛网

一项发表在《柳叶刀》的最新研究,三名奥地利男子接受了世界首例新技术“仿生重建术”的治疗,该手术可帮助他们通过一个机器人修复手臂来执行自己意愿之事。这三例患者遭受臂丛神经损伤的困扰多年,在骑摩托车与攀爬时手部功能受限。 这项新技术由来自维也纳大学基督多普勒实验室主任Oskar Aszmann教授发明,该技术联合了神经肌肉传导等技术,将其与机器人辅助技术完美结合。随着康复的推移,该技术对三位受试

一项发表在《柳叶刀》的最新研究,三名奥地利男子接受了世界首例新技术“仿生重建术”的治疗,该手术可帮助他们通过一个机器人修复手臂来执行自己意愿之事。这三例患者遭受臂丛神经损伤的困扰多年,在骑摩托车与攀爬时手部功能受限。

这项新技术由来自维也纳大学基督多普勒实验室主任Oskar Aszmann教授发明,该技术联合了神经肌肉传导等技术,将其与机器人辅助技术完美结合。随着康复的推移,该技术对三位受试者重建了高水平的肢体功能,实现了正常日常活动的目标。

Aszmann教授解释说,“实际上,臂丛神经撕脱伤代表着机体内部的联系被切断,在神经控制下不可逆的将手部分离。现有的手术技术对这种伤害的治疗效果较差,甚至无效,最终导致手部功能不佳。”“极具科学性突破的是,这一技术通过移植肌肉对神经传导建立了新的传输信号,这些信号会被传导至机电一体化的手臂功能中。”

在截肢前,所有的受试者用了平均9个月的时间进行认知培训,首先是实现肌肉的活动性,其次是使用电信号控制虚拟手臂。一旦他们能够对这一虚拟条件进行控制,他们就要练习使用混合手臂——与一个夹板状装置项链的假体手臂,以此修复无功能手臂。

术后三个月,机器人装置在三位受试者的手臂功能中扮演了可喜的角色,提高了他们的生活质量,并且疼痛感轻微。这也是首次,这些受试者能够完成诸如捡球、从用水壶倒水、使用钥匙、用小刀切食物或用两只手进行撤销按钮操作等日常活动。

臂丛神经损伤发生时,起源于颈部及分支、形成控制上肢(包括肩,手臂,前臂,和手的运动和感觉)的神经网络受损。臂丛神经损伤常常发生于高速撞击的创伤中,特别是摩托车事故、橄榄球和美式足球这样的碰撞运动中。

根据Aszmann教授的说法,“目前为止,仿生学重建术至能在维也纳医学中心完成。不过,目前没有技术或手术限制能够对这种方式加以阻碍。”

Simon Kay教授是英国首例实施手臂移植的术者,他和Daniel Wilk在一则评论中写到。“当前的发明的这一仿生学重建技术振奋人心,因为它为修复系统提供了看似难以实现的其他神经输入路径。不过,该技术的最终结果还要依赖对长期结果的观察,包括对使用范围的评估、负重研究等,而且一旦受损所需要的修复情况等,都要进行随访后才能得知。”

原始出处:

Aszmann OC1, Roche AD2, Salminger S2, Paternostro-Sluga T3, Herceg M3, Sturma A2, Hofer C4, Farina D5.Bionic reconstruction to restore hand function after brachial plexus injury: a case series of three patients.Lancet. 2015 Feb 24. pii: S0140-6736(14)61776-1. doi: 10.1016/S0140-6736(14)61776-1. [Epub ahead of print]

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2021165, encodeId=44402021165f2, content=<a href='/topic/show?id=f8fc256219a' target=_blank style='color:#2F92EE;'>#仿生重建术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25621, encryptionId=f8fc256219a, topicName=仿生重建术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKjqGDO7icVKUiaT7urgwXvnvzWtp0fMFU46Xfib8oavFKygiaWtibXReS6ZUh3PImsNicGAwTO5HXxoicnA/132, createdBy=ee262500130, createdName=ms7474195563676018, createdTime=Sat Mar 07 15:33:00 CST 2015, time=2015-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828020, encodeId=96d518280208a, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 28 00:33:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20880, encodeId=444c208809c, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:39:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20134, encodeId=56f5201349e, content=好高大上的, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3r6Ir8EADbw8kut6NgpfYKrksLd7rsf9GSZGCUZkpHosu8Jsibzk64KSuO8dFfOW7J5kW4bjib4eI/0, createdBy=d0201619051, createdName=吴颖, createdTime=Sat Apr 11 08:17:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18692, encodeId=66c3186928e, content=没看懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLBzoPY0a1ZQrECBF90v8AkFiaxRlNpGj1mLzD1B7ibnyBjmDEjiauBSDpOw6w4tI7YxmjdWaIW0SXL4/0, createdBy=35951605658, createdName=等你一年又一年, createdTime=Tue Mar 24 00:25:00 CST 2015, time=2015-03-24, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2021165, encodeId=44402021165f2, content=<a href='/topic/show?id=f8fc256219a' target=_blank style='color:#2F92EE;'>#仿生重建术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25621, encryptionId=f8fc256219a, topicName=仿生重建术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKjqGDO7icVKUiaT7urgwXvnvzWtp0fMFU46Xfib8oavFKygiaWtibXReS6ZUh3PImsNicGAwTO5HXxoicnA/132, createdBy=ee262500130, createdName=ms7474195563676018, createdTime=Sat Mar 07 15:33:00 CST 2015, time=2015-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828020, encodeId=96d518280208a, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 28 00:33:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20880, encodeId=444c208809c, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:39:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20134, encodeId=56f5201349e, content=好高大上的, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3r6Ir8EADbw8kut6NgpfYKrksLd7rsf9GSZGCUZkpHosu8Jsibzk64KSuO8dFfOW7J5kW4bjib4eI/0, createdBy=d0201619051, createdName=吴颖, createdTime=Sat Apr 11 08:17:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18692, encodeId=66c3186928e, content=没看懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLBzoPY0a1ZQrECBF90v8AkFiaxRlNpGj1mLzD1B7ibnyBjmDEjiauBSDpOw6w4tI7YxmjdWaIW0SXL4/0, createdBy=35951605658, createdName=等你一年又一年, createdTime=Tue Mar 24 00:25:00 CST 2015, time=2015-03-24, status=1, ipAttribution=)]
    2015-08-28 howi
  3. [GetPortalCommentsPageByObjectIdResponse(id=2021165, encodeId=44402021165f2, content=<a href='/topic/show?id=f8fc256219a' target=_blank style='color:#2F92EE;'>#仿生重建术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25621, encryptionId=f8fc256219a, topicName=仿生重建术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKjqGDO7icVKUiaT7urgwXvnvzWtp0fMFU46Xfib8oavFKygiaWtibXReS6ZUh3PImsNicGAwTO5HXxoicnA/132, createdBy=ee262500130, createdName=ms7474195563676018, createdTime=Sat Mar 07 15:33:00 CST 2015, time=2015-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828020, encodeId=96d518280208a, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 28 00:33:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20880, encodeId=444c208809c, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:39:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20134, encodeId=56f5201349e, content=好高大上的, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3r6Ir8EADbw8kut6NgpfYKrksLd7rsf9GSZGCUZkpHosu8Jsibzk64KSuO8dFfOW7J5kW4bjib4eI/0, createdBy=d0201619051, createdName=吴颖, createdTime=Sat Apr 11 08:17:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18692, encodeId=66c3186928e, content=没看懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLBzoPY0a1ZQrECBF90v8AkFiaxRlNpGj1mLzD1B7ibnyBjmDEjiauBSDpOw6w4tI7YxmjdWaIW0SXL4/0, createdBy=35951605658, createdName=等你一年又一年, createdTime=Tue Mar 24 00:25:00 CST 2015, time=2015-03-24, status=1, ipAttribution=)]
    2015-04-12 x35042875

    患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2021165, encodeId=44402021165f2, content=<a href='/topic/show?id=f8fc256219a' target=_blank style='color:#2F92EE;'>#仿生重建术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25621, encryptionId=f8fc256219a, topicName=仿生重建术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKjqGDO7icVKUiaT7urgwXvnvzWtp0fMFU46Xfib8oavFKygiaWtibXReS6ZUh3PImsNicGAwTO5HXxoicnA/132, createdBy=ee262500130, createdName=ms7474195563676018, createdTime=Sat Mar 07 15:33:00 CST 2015, time=2015-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828020, encodeId=96d518280208a, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 28 00:33:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20880, encodeId=444c208809c, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:39:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20134, encodeId=56f5201349e, content=好高大上的, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3r6Ir8EADbw8kut6NgpfYKrksLd7rsf9GSZGCUZkpHosu8Jsibzk64KSuO8dFfOW7J5kW4bjib4eI/0, createdBy=d0201619051, createdName=吴颖, createdTime=Sat Apr 11 08:17:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18692, encodeId=66c3186928e, content=没看懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLBzoPY0a1ZQrECBF90v8AkFiaxRlNpGj1mLzD1B7ibnyBjmDEjiauBSDpOw6w4tI7YxmjdWaIW0SXL4/0, createdBy=35951605658, createdName=等你一年又一年, createdTime=Tue Mar 24 00:25:00 CST 2015, time=2015-03-24, status=1, ipAttribution=)]
    2015-04-11 吴颖

    好高大上的

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2021165, encodeId=44402021165f2, content=<a href='/topic/show?id=f8fc256219a' target=_blank style='color:#2F92EE;'>#仿生重建术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25621, encryptionId=f8fc256219a, topicName=仿生重建术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKjqGDO7icVKUiaT7urgwXvnvzWtp0fMFU46Xfib8oavFKygiaWtibXReS6ZUh3PImsNicGAwTO5HXxoicnA/132, createdBy=ee262500130, createdName=ms7474195563676018, createdTime=Sat Mar 07 15:33:00 CST 2015, time=2015-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828020, encodeId=96d518280208a, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Aug 28 00:33:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20880, encodeId=444c208809c, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:39:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20134, encodeId=56f5201349e, content=好高大上的, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3r6Ir8EADbw8kut6NgpfYKrksLd7rsf9GSZGCUZkpHosu8Jsibzk64KSuO8dFfOW7J5kW4bjib4eI/0, createdBy=d0201619051, createdName=吴颖, createdTime=Sat Apr 11 08:17:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18692, encodeId=66c3186928e, content=没看懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLBzoPY0a1ZQrECBF90v8AkFiaxRlNpGj1mLzD1B7ibnyBjmDEjiauBSDpOw6w4tI7YxmjdWaIW0SXL4/0, createdBy=35951605658, createdName=等你一年又一年, createdTime=Tue Mar 24 00:25:00 CST 2015, time=2015-03-24, status=1, ipAttribution=)]
    2015-03-24 等你一年又一年

    没看懂

    0