SCI REP:长期睡眠持续时间是中国人群中心房颤动事件独立危险因素:前瞻性队列研究

2017-06-19 MedSci MedSci原创

我们的Kailuan队列研究结果表明,长期睡眠时间可能会导致中国人口的房颤风险增加。 鼓励和支持个人每晚进行7小时睡眠可能对于阻止中国房颤患病率日益增长有重大的有益影响。

截至目前为止,有关睡眠持续时间与心房颤动事件之间关系的信息有限。我们的目的是使用Kailuan研究的队列资料,调查中国人口中的这一关系。该分析包括在基线调查中没有心房颤动的87,693名参与者(年龄范围,18-98岁)。参加者根据自我报告的睡眠时间分为三类:≤6.0小时,7小时(参考),≥8.0小时。通过标准的12导联心电图和自我报告的历史来进行房颤诊断。根据睡眠持续时间,使用Cox比例风险模型计算心房颤动的风险比(HR)和置信区间(CI)。在7.89(范围,6.36-8.57)年的中位随访期间,发生了322例房颤。从睡眠时间的最低到最高,利用7小时睡眠作为参考组,房颤的多变量调整HR(95%CI)分别为为1.07(0.75-1.53),1.0(ref)和1.50(1.07-2.10)。次要分析显示睡眠持续时间和性别之间存在相互作用的迹象,以及打鼾对房颤发生风险的影响(p = 0.75 / 0.25)。我们认为长期睡眠持续时间可能是心房颤动事件的潜在预测因子/标志物。

总结:总而言之,我们的Kailuan队列研究结果表明,长期睡眠时间可能会导致中国人口的房颤风险增加。 鼓励和支持个人每晚进行7小时睡眠可能对于阻止中国房颤患病率日益增长有重大的有益影响。

原文出处:

Shouling Wu,et al.Long Sleep Duration Is an Independent Risk Factor for Incident Atrial Fibrillation in a Chinese Population: A Prospective Cohort Study.[J]Scientific Reports 7, Article number:3679(2017),doi:10.1038/s41598-017-04034-8

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    2017-06-21 zhwj
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