J Periodontol:哮喘患者牙周病的风险:一项基于大范围人群的回顾性队列研究

2017-08-16 MedSci MedSci原创

目前研究已经报道了哮喘和口腔疾病之间的关联,包括牙周病。这项回顾性研究的目的是调查哮喘患者牙周病的风险。

目前研究已经报道了哮喘和口腔疾病之间的关联,包括牙周病。这项回顾性研究的目的是调查哮喘患者牙周病的风险。

使用台湾全民健康保险索赔数据和无牙周病史患者数据,确定了2000年至2010年新诊断的19,206例哮喘患者。对于每个病例,从一般人群中随机抽取4例无哮喘和牙周病史的对照组患者,按性别,年龄,诊断年份进行频率匹配(分类匹配)(n = 76,824)。两组同步进行,以监测牙周病的发生,直至2011年年底。使用Cox比例风险回归分析估计牙周病的调整风险比(aHRs)。

结果:哮喘组牙周病总发生率比对照组高1.18倍(P <0.001)。每年至少三次紧急访问的患者,与平均不到一次的访问相比,患有牙周病的aHR达55.9%(95%置信区间[CI] = 50.6?61.7)。每年入院至少三次的患者,牙周病aHR(51.8)。此外,使用吸入性皮质类固醇(ICS)治疗的哮喘患者比非用户具有更高的aHR(aHR = 1.12; 95%CI = 1.03至1.23)。

结论:在研究人群中,哮喘患者发生牙周病的风险较高。有紧急医疗需求或入院治疗以及ICS治疗者的风险要大得多。

原始出处:

Te-Chun Shen, Pei-Ying Chang, Cheng-Li Lin, et al. Risk of Periodontal Disease in Patients With Asthma: A Nationwide Population-Based Retrospective Cohort Study. Journal of periodontology. 2017 August. doi: 10.1902/ jop.2017.160414

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