新英格兰医学杂志病例:房颤患者皮肤变色,原来是因这种药

2020-01-19 岱西 中国循环杂志

一位房颤并合并高血压的81岁男子,摔倒后急诊就诊。体格检查时发现,患者面部有蓝色和灰色色素沉着,鼻部、脸部和前额均变色。图1 患者面部的蓝色和灰色色素沉着患者跌倒后无受伤,自称这种皮肤变色存在已久。心电图显示有房颤,心率68次/min。服用胺碘酮治疗已有15年。同时服用的药物还要阿哌沙班、雷米普利、比索洛尔、氨氯地平。色素沉着是胺碘酮罕见的不良反应,或会随着药物的停用而减轻。跌倒可归因于体位性低血

一位房颤并合并高血压的81岁男子,摔倒后急诊就诊。

体格检查时发现,患者面部有蓝色和灰色色素沉着,鼻部、脸部和前额均变色。



图1 患者面部的蓝色和灰色色素沉着

患者跌倒后无受伤,自称这种皮肤变色存在已久。

心电图显示有房颤,心率68次/min。服用胺碘酮治疗已有15年。同时服用的药物还要阿哌沙班、雷米普利、比索洛尔、氨氯地平。

色素沉着是胺碘酮罕见的不良反应,或会随着药物的停用而减轻。跌倒可归因于体位性低血压。住院期间,患者药物进行了调整,包括停用胺碘酮。

随访6个月,皮肤变色持续存在。该患者报告无再次跌倒或发生伴快速心室反应的房颤。

来源:Robert P. Murphy,et al. Skin Discoloration from Amiodarone.N Engl J Med 2020.1.18.

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    2020-01-19 心介

    房颤,临床上碰到很多哦

    0

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