J Asthma Allergy:慢性鼻窦炎伴鼻息肉过敏性表型的临床和放射学特征分析

2020-12-02 AlexYang MedSci原创

之前的研究已经阐述了慢性鼻窦炎(CRS)和中央室特应性疾病(CCAD)的过敏表型。CCAD是CRS患者的一种放射学表型,表现为过敏引起的中央粘膜疾病。慢性鼻窦炎伴鼻息肉(CRSwNP)患者亚群尚未很好

之前的研究已经阐述了慢性鼻窦炎(CRS)和中央室特应性疾病(CCAD)的过敏表型。CCAD是CRS患者的一种放射学表型,表现为过敏引起的中央粘膜疾病。慢性鼻窦炎伴鼻息肉(CRSwNP)患者亚群尚未很好的进行表征。最近,有研究人员描述了出现CRSwNP过敏表型患者的临床和放射学特征。

研究人员在一家三甲医院进行了一个代表性的研究。招募了诊断为CRSwNP的成人患者,且这些患者同时进行了过敏学和放射学评估。研究共包括了38名患者。结果表明,与非过敏组和非CCAD组相比,过敏组和CCAD组的症状、内镜和CTPNS评分均较高。"需要擦鼻涕 "这一症状在过敏组与非过敏组(P=0.01)、CCAD组与非CCAD组(P=0.02)之间有统计学显著差异。另外,过敏和CCAD的内镜评分均有显著差异(过敏vs非过敏,p=0.01;CCADvs非CCAD,p=0.03);过敏和CCAD的CT评分均有显著差异(过敏vs非过敏,p=0.02;CCADvs非CCAD,p=0.02)。所有CCAD患者的评分都比非CCAD差(LK评分,p=0.03;LM评分,p=0.02)。过敏患者比非过敏和非CCAD患者有更多的鼻甲息肉样病变(左中鼻甲,p=0.141;右中鼻甲,p=0.074)和CCAD(左中鼻甲,p=0.017;右中鼻甲,p=0.009)。

CCAD与非CCAD中鼻窦比较

最后,研究人员指出,过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。

原始出处:

Baharudin Abdullah, Selvamalar Vengathajalam, Mohd Khairi Md Daud et al. The Clinical and Radiological Characterizations of the Allergic Phenotype of Chronic Rhinosinusitis with Nasal Polyps. J Asthma Allergy. 2020

 

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535289, encodeId=1b2f15352896b, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904645, encodeId=63149046454a, content=过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Thu Dec 03 17:44:49 CST 2020, time=2020-12-03, status=1, ipAttribution=)]
    2021-09-29 skhzy
  4. 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href='/topic/show?id=be7453e38d2' target=_blank style='color:#2F92EE;'>#慢性鼻窦炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53738, encryptionId=be7453e38d2, topicName=慢性鼻窦炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385643, encodeId=1d5b138564323, content=<a href='/topic/show?id=b3d05e3382b' target=_blank style='color:#2F92EE;'>#放射学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57338, encryptionId=b3d05e3382b, topicName=放射学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3bb506, createdName=kkunny, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535289, encodeId=1b2f15352896b, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904645, encodeId=63149046454a, content=过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Thu Dec 03 17:44:49 CST 2020, time=2020-12-03, status=1, ipAttribution=)]
    2021-01-14 jipenghui456

    学习了,谢谢

    0

  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535289, encodeId=1b2f15352896b, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904645, encodeId=63149046454a, content=过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Thu Dec 03 17:44:49 CST 2020, time=2020-12-03, status=1, ipAttribution=)]
    2020-12-04 膀胱癌
  6. 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  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535289, encodeId=1b2f15352896b, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904645, encodeId=63149046454a, content=过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Thu Dec 03 17:44:49 CST 2020, time=2020-12-03, status=1, ipAttribution=)]
    2020-12-04 kkunny
  8. 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    2020-12-04 tastas
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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535289, encodeId=1b2f15352896b, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Fri Dec 04 13:41:06 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904645, encodeId=63149046454a, content=过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Thu Dec 03 17:44:49 CST 2020, time=2020-12-03, status=1, ipAttribution=)]
    2020-12-03 Jessie Zhang

    过敏性CRSwNP的临床和放射学疾病负担更重。须对过敏患者进行优化治疗来获得较好的治疗效果。

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