JPD:中国50万人研究:爱吸烟和喝茶的人,长期患帕金森的风险如何?

2022-05-14 Freeman MedSci原创

吸烟和每日饮茶与PD的风险独立成反比。

帕金森病(PD)是中老年人群中常见的神经性疾病;其病因尚不清楚。26年来,PD患者的数量增加了一倍多,从1990年的250万患者增加到2016年的610万,给社会和家庭带来了沉重负担。

图1: 论文封面图

以前的荟萃分析,包括主要的病例对照研究,报道了吸烟是PD的保护性因素。然而,这种追溯性的病例对照研究设计的一个重要局限性是有很大的机会出现反向因果关系偏差。为数不多的前瞻性研究主要是在西方人群中进行的,而且病例数量不多。

一些实验研究表明,茶叶中的天然生物活性成分,如多酚、茶氨酸和咖啡因,可能对PD等神经退行性疾病带来神经保护作用。一项包括4项病例对照和4项前瞻性研究的荟萃分析报告了茶叶消费与PD风险降低之间的线性关系,因此,仅有前瞻性研究的汇总结果。然而,中国人口的前瞻性证据很少,因为中国人有悠久的饮茶传统。

藉此,北京大学的Jia Niea等人,在中国China Kadoorie Biobank(CKB对50万成年人的研究中,前瞻性地研究饮茶和吸烟与PD风险的独立和联合关系。

他们在中国嘉道理生物库(CKB)研究自2004年起在中国10个地区招募了512,725名30至79岁的参与者。在基线时收集了吸烟和饮茶的信息,通过与国家健康保险系统和死亡登记处的联系确定了PD病例。采用Cox比例危害模型估计多变量调整后的危险比(HRs)和相应的95%置信区间(CIs)。

图2: 论文结果图

他们发现:在中位数为10.8年的随访期间,共记录了922例PD病例。与从未喝过茶的参与者相比,每天喝茶的HR(95%CI)为0.68(0.55,0.84)。

与从不吸烟或偶尔吸烟的参与者相比,目前吸烟者的HR(95%CI)为0.66(0.53,0.82)。那些有吸烟和喝茶的集群习惯的人,其PD风险比没有消费的人低38%(HR = 0.62; 95%CI: 0.49, 0.79)。

然而,饮茶和吸烟对PD风险没有明显的乘法或加法交互作用。

该研究的重要意义在于发现了:吸烟和每日饮茶与PD的风险独立成反比。


原文出处:
for the China Kadoorie Biobank (CKB) Collaborative Group, Nie J, Liu C, et al. Independent and Joint Associations of Tea Consumption and Smoking with Parkinson’s Disease Risk in Chinese Adults. JPD. Published online May 2, 2022:1-10. doi:10.3233/JPD-223148.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (11)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-16 ms6000001842832174

    上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-16 陈年小医

    要想健康又长寿,抽烟喝酒吃肥肉?

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-16 1466b254m69暂无昵称

    文章作者跟烟草集团有利益相关吗?

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-16 大光

    结果不是那么严谨

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-15 hbwxf
  6. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-15 Kerry will

    结论是否定了吗?

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-15 weigq

    是否重新开始吸烟?

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-15 ms3000002046518395

    学习

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-15 顾纪新

    ******

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1219976, encodeId=ffe912199e67f, content=上联:我用了五分钟时间看了篇不严谨的文章,不知所云 下联:又花了3分钟写了不客气的评论,毫无意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60546555317, createdName=ms6000001842832174, createdTime=Mon May 16 11:46:15 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219943, encodeId=e414121994354, content=要想健康又长寿,抽烟喝酒吃肥肉?, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKoXgLD7CpoyhDTq3KibAeqrA5aAtkCJWVlgO2Tpuj5aicNnYefGMXjP46OPpljUFMf8GDvGkNgQ4LA/132, createdBy=91385314047, createdName=陈年小医, createdTime=Mon May 16 10:18:19 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219920, encodeId=dc9b121992087, content=文章作者跟烟草集团有利益相关吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11ad5137230, createdName=1466b254m69暂无昵称, createdTime=Mon May 16 09:10:55 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219887, encodeId=5d77121988e57, content=结果不是那么严谨, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJbibsxJPyM36vENWicvqMe2IS4ibZYHPAXpaHlhYTjibOUAV1yk2L9TWnMuUe686pjGzpiaDZdfjmaIhQ/132, createdBy=93121739292, createdName=大光, createdTime=Mon May 16 02:04:38 CST 2022, time=2022-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402439, encodeId=e0711402439e6, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun May 15 13:16:16 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219752, encodeId=81b81219e52b4, content=结论是否定了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb428154553, createdName=Kerry will, createdTime=Sun May 15 11:56:19 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219737, encodeId=65f41219e373c, content=是否重新开始吸烟?, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun May 15 10:09:37 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219714, encodeId=1c3c1219e14da, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=56d28118192, createdName=ms3000002046518395, createdTime=Sun May 15 08:27:10 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219700, encodeId=f8db1219e0012, content=******, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b1c1969387, createdName=顾纪新, createdTime=Sun May 15 05:52:11 CST 2022, time=2022-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219676, encodeId=486612196e6b9, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat May 14 22:45:25 CST 2022, time=2022-05-14, status=1, ipAttribution=)]
    2022-05-14 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

相关资讯

Lancet Neurol:阿朴吗啡可有效改善帕金森病患者的睡眠障碍

夜间皮下注射阿朴吗啡可改善帕金森病患者的睡眠障碍

Neurology:神经丝光与帕金森病的发展和严重程度的关联

血液生物标记物可能有助于早期识别帕金森氏病(PD)、帕金森氏症及PD相关不良结局。近日,研究人员发现Nf-L与临床帕金森病、帕金森症状和身体功能下降有关。Nf-L或为神经退行性变潜在生物标记物。

JPD:人格测试,有助于帕金森病基本分类

早期帕金森病患者的性格使我们能够识别3种患者的表型

Neurology:表现为帕金森和痴呆的AVM和直窦血栓形成

FLAIR显示双侧丘脑高信号和肿胀(A,箭头),SWI低信号(B,箭头),提示双丘脑出血和水肿。

npj Parkinsons Dis :便秘程度,可预测帕金森患者的临床结局

早期便秘可能预示着神经退行性病变的加速发展。

拓展阅读

European Radiology:弥散基础频谱成像检测早期帕金森病黑质和白质束的病理改变

为了解决弥散张量成像的局限性,研究发展了弥散基谱成像 (DBSI)以粗量化各向异性扩散张量反映轴突的完整性,其在多种中枢神经系统疾病中的敏感性和准确性已被证实。

帕金森病睡眠量表修订版(PDSS-2)

帕金森病睡眠量表修订版(PDSS-2)

神经科一周速递:热点解读进展大盘点!

一周热点分享 ,紧跟神经科学前沿,让每一次诊疗都更精准,点击立即查看!

早发性帕金森病临床变异性|疑难探究

发病年龄小于50岁的帕金森病被称为早发型帕金森病,发病年龄在21~50为青年型帕金森病,21岁以前发病的被称为少年型帕金森病。

帕金森病:想睡个好觉太难!

帕金森病(PD)患者昼夜节律的改变不仅会影响睡眠-觉醒周期调节,同样会对非运动症状造成影响。

论文解读|Huifang Shang教授团队最新研究揭示与帕金森病相关的PLXNA1基因的罕见变异

研究揭示了与神经系统疾病和帕金森综合症有关的PLXNA1基因罕见变异。

2024 NICE 诊断指南:帕金森病远程监测设备 [DG51]

英国国家卫生与临床优化研究所(NICE,National Institute for Health and Clinical Excellence) · 2024-01-25

2023 NICE 技术鉴定指南:左旋多巴/卡比多巴组合治疗伴有运动症状的晚期帕金森病[TA934]

英国国家卫生与临床优化研究所(NICE,National Institute for Health and Clinical Excellence) · 2023-11-29

帕金森病患者睡眠障碍评估与护理干预的最佳证据总结

浙江中医药大学护理学院 · 2023-08-10

早中期帕金森病患者运动管理的最佳证据总结

山东第一医科大学附属省立医院老年神经内科 · 2023-05-10