消化

订阅

MedSci主页 / 所有栏目 / 消化

Science子刊：惊人发现！肠道细菌或可改变肠道和大脑的功能

2017-03-03 生物谷 生物谷

肠道细菌肠道易激综合征大脑功能无菌小鼠粪便移植
关注

日前，一项刊登在国际杂志Science Translational Medicine上的研究报告中，来自麦克马斯特大学的研究人员通过研究发现，肠道中的细菌或许能够影响肠道易激综合征（irritable bowel syndrome，IBS）患者机体肠道和行为的症状，相关研究或为研究人员开发

图片来源：medicalxpress.com

日前，一项刊登在国际杂志Science Translational Medicine上的研究报告中，来自麦克马斯特大学的研究人员通过研究发现，肠道中的细菌或许能够影响肠道易激综合征（irritable bowel syndrome，IBS）患者机体肠道和行为的症状，相关研究或为研究人员开发微生物定向疗法提供了新的思路和见解。

肠道易激综合征是一种常见的胃肠道疾病，其会影响机体的大肠组织，而患者也会遭受腹痛以及排便习惯的改变，比如腹泻和便秘等，通常患者还会伴随出现慢性焦虑和抑郁症等，当前的疗法目的就是改善患者的症状，但患者的病因并不清楚，所以这些疗法的疗效显得非常有限。

本文研究中研究人员希望通过研究能够深入阐明是否发生腹泻的IBS患者机体的粪便微生物能够影响受体小鼠机体的肠道和大脑功能，利用粪便移植，研究人员就将IBS患者（焦虑或者非焦虑患者）机体的微生物群落转移到了无菌小鼠机体中，随后研究者发现，相比接受健康个体微生物的小鼠而言，接受IBS患者机体中微生物的小鼠慢慢会表现出肠道功能和行为的改变。

研究人员发现，通过粪便移植所影响的小鼠的疾病情况包括胃肠道症状、肠屏障功能障碍低度炎症以及焦虑样行为等。文章第一作者Giada De Palma说道，这是一项标志性研究，因为其超越了一种简单的关联性研究，而且本文研究发现了肠道微生物的改变会同时影响IBS患者机体肠道和行为的反应。

同时，本文研究也为研究人员开发靶向作用肠道微生物的新型疗法，以及寻找诊断IBS的生物标志物提供了新的线索；研究者总结道，本文研究或许提出了一种可能性，即包括益生菌疗法等微生物定向疗法或许能够有效治疗患者的肠道症状，同时也能够有效患者IBS患者的疾病表现。更有意思的是，研究者还发现，肠道中的微生物或许还能够影响大脑的功能，这就表明，肠道微生物或许在多种脑部障碍的发生过程中扮演着重要角色，比如焦虑、自闭症、帕金森疾病以及多发性硬化症等疾病。

原始出处：

Giada De Palma, Michael D. J. Lynch, Jun Lu, et al. Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice, Science Translational Medicine  01 Mar 2017. DOI: 10.1126/scitranslmed.aaf6397

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (9)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-21 喜婷

    学习了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-16 喜婷

    学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-11 喜婷

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-11 小帆儿

    感谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-10 simayunhe

    进一步发展，谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-05 1e0ece0dm09(暂无匿称)

    谢谢分享

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-04 listen318

    #肠道细菌#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-04 jichang

    #SCIE#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=181711, encodeId=dedb181e1112, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Tue Mar 21 14:35:57 CST 2017, time=2017-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180267, encodeId=e3f218026ef1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Thu Mar 16 08:12:52 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179167, encodeId=d1ee1e9167c1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKfcA3xZnott5TnvcnGrdO58uy0RP4NgPa0Qz8FibHlolypPLEmmcGicSPMJVWQKbRkAY8UVZlFRtGw/132, createdBy=c67f2030047, createdName=喜婷, createdTime=Sat Mar 11 20:37:08 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=179126, encodeId=f1dd1e91260e, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87dd2033339, createdName=小帆儿, createdTime=Sat Mar 11 12:51:56 CST 2017, time=2017-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178862, encodeId=5b401e8862c6, content=进一步发展，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCYbPBa7AiaIy1pMpp7CF9lHORw4icR9GOrMO6RVNCb1qSUSY9TFBzW5zlrpDia0HKafiarjvcweMaVdg/0, createdBy=f1d61928636, createdName=simayunhe, createdTime=Fri Mar 10 13:50:39 CST 2017, time=2017-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178632, encodeId=02021e863273, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Mar 05 17:43:36 CST 2017, time=2017-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369874, encodeId=04c013698e4a4, content=<a href='/topic/show?id=4f4081e22b0' target=_blank style='color:#2F92EE;'>#肠道细菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81722, encryptionId=4f4081e22b0, topicName=肠道细菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1375495, encodeId=f25713e549508, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Sat Mar 04 23:33:00 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178568, encodeId=fed21e856857, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Mar 04 11:22:44 CST 2017, time=2017-03-04, status=1, ipAttribution=)]
    2017-03-04 1e0ece0dm09(暂无匿称)

    谢谢分享

    0

相关资讯

Science：人体细胞又添新类型，可“清洗”肠道细菌

我们肠道内的微生物群对于机体健康的维持具有重要意义，但若得不到有效调节和控制，则会成为健康隐患，可能引发腹泻、腹胀、炎症性肠炎等病症。 为此，我们的肠道表面分泌有一层保护性的粘液，以防止肠道内细菌直接侵入肠壁组织而引发炎症反应。这些粘液的主要成分为粘蛋白，由肠壁上的杯状细胞（goblet cell）分泌。然而，这层粘液并不是密不通风的，有时也会被少数细菌越过，成为“漏网之鱼”。 ▲肠壁上的

Cell：新发现的原生生物让宿主免受肠道细菌感染

尽管细菌经常是肠道微生物组的明星，但是不断涌现的研究描画出一种更加复杂的情形：来自不同生物界的微生物积极地相互合作或者彼此相互抵抗。在一项新的研究中，来自美国西奈山伊坎医学院的研究人员发现一个例子：一种新发现的原生生物阻止它的宿主小鼠遭受肠道细菌感染。相关研究结果发表在2016年10月6日那期Cell期刊上，论文标题为“Host-Protozoan Interactions Protect fro

Cell：重磅！一种肠道细菌有望逆转自闭症症状

在一项新的研究中，来自美国贝勒医学院的研究人员报道，缺乏一种特定的肠道细菌物种导致小鼠社交能力不足（social deficit）。这些社交能力不足令人想起人类自闭症谱系障碍（autism spectrum disorder, ASD）的症状。通过将这种细菌物种添加到受影响的小鼠肠道中，研究人员能够逆转这些小鼠的一些社交行为问题。相关研究结果发表在2016年6月16日那期Cell期刊上，论文

Nature：肠道微生物菌群不平衡增加糖尿病风险

目前，科学家们认为导致胰岛素耐受性（insulin resistance）的主要因子是体重超重和缺乏身体活动。一项新的由欧盟资助的一个欧洲-中国团队开展的被称作MetaHit的突破性研究发现特定的肠道细菌不平衡能够导致胰岛素耐受性，从而导致2型糖尿病等健康问题的风险增加。相关研究结果于2016年7月13日在线发表在Nature期刊上，论文标题为“Human gut microbes impact

减肥老反弹？都怪肠道细菌

一项对小鼠的研究表明，高脂饮食会改变（肠道）菌群并且抑制过胖者自身利用黄酮类化合物的能力。大家肯定对以下情景很熟悉：我们好不容易减下去几斤，然而随后体重又反弹，如此反复。最近，Nature 杂志报道的一项研究显示，可能是你肠道中的细菌造成了这种“悠悠球效应”。由以色列魏茨曼科学研究所的 Eran Elinav 带领的科学家团队利用小鼠研究为什么减肥会适得其反。他们发现，高脂和低脂饮食的循环会改变小

BBC称粪便实为“金矿”：人粪制药比手术都管用

英媒称，“When Doody Calls”是一家专门清理狗狗粪便的公司。创始人名叫玛丽·艾伦·莱维，这家公司创办于2001年，目前拥有450家客户。这是一个新兴的成长型行业，没有人测算过这个行业的全球规模，但莱维是动物粪便专家协会的理事，该协会目前有90家会员企业，专门在北美各地收集宠物粪便。 据英国广播公司网站7月7日报道，这绝非唯一一家与宠物粪便有关的公司，如果说这个有些“肮脏”的行业有什