Complement Ther Clin Pract:子宫肌瘤患者是不是要多吃维生素D?

2021-01-19 MedSci原创 MedSci原创

子宫肌瘤是女性生殖系统的常见肿瘤。有症状的子宫肌瘤需要根据症状的严重程度进行手术或其他治疗。最近,维生素D已被确定为一种潜在的抗肿瘤化合物,可抑制子宫肌瘤细胞,减少肌瘤病变。 最近的证据表明,维生素D

子宫肌瘤是女性生殖系统的常见肿瘤。有症状的子宫肌瘤需要根据症状的严重程度进行手术或其他治疗。最近,维生素D已被确定为一种潜在的抗肿瘤化合物,可抑制子宫肌瘤细胞,减少肌瘤病变。 最近的证据表明,维生素D血清缺乏与子宫肌瘤风险增加之间存在相关性。近日,发表于Complement Ther Clin Pract的一项随机、对照双盲研究中,研究人员发现摄入维生素D短期内可减小子宫肌瘤的体积,但其长期疗效仍需评估。

研究人员纳入符合条件的女性,随机分配分别接受维生素D或安慰剂12周,主要结果是子宫肌瘤体积的变化。

 

结果显示,维生素组患者的子宫肌瘤体积无统计学意义的减少[平均差异(MD):-0.71,95%置信区间(CI):-0.1~1.53,P=0.085],但是对照组患者的子宫肌瘤体积显著增加(MD:2.53,95%CI:1.9~4.05,P=0.001)。

综上所述,该研究结果表明,摄入维生素D可抑制子宫肌瘤的生长,但其长期效果仍不清楚。

 

原始出处:

 

Somayye Arjeh, Fatemeh Darsareh, et al., Effect of oral consumption of vitamin D on uterine fibroids: A randomized clinical trial. Complement Ther Clin Pract. 2020 May;39:101159. doi: 10.1016/j.ctcp.2020.101159.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1209433, encodeId=2586120943347, content=剂量是多少呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erFE1IgJcfnOGsibGrna95eBt7ELNXK85krdEJ0RAYjiaU11PyPj40c1BsktlfCfLH0n9jm99iahR06w/132, createdBy=05422454711, createdName=慧子, createdTime=Fri Apr 08 01:51:13 CST 2022, time=2022-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783562, encodeId=8d561e83562cd, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Aug 17 23:53:27 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773339, encodeId=a2d31e733398d, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Aug 25 17:53:27 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918409, encodeId=341991840944, content=已读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Wed Jan 20 14:51:22 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918306, encodeId=f0ea918306af, content=摄入维生素D可抑制子宫肌瘤的生长。<a href='/topic/show?id=53144518948' target=_blank style='color:#2F92EE;'>#子宫肌瘤#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45189, encryptionId=53144518948, topicName=子宫肌瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 10:26:41 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2022-04-08 慧子

    剂量是多少呢

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1209433, encodeId=2586120943347, content=剂量是多少呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erFE1IgJcfnOGsibGrna95eBt7ELNXK85krdEJ0RAYjiaU11PyPj40c1BsktlfCfLH0n9jm99iahR06w/132, createdBy=05422454711, createdName=慧子, createdTime=Fri Apr 08 01:51:13 CST 2022, time=2022-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783562, encodeId=8d561e83562cd, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Aug 17 23:53:27 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773339, encodeId=a2d31e733398d, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Aug 25 17:53:27 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918409, encodeId=341991840944, content=已读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Wed Jan 20 14:51:22 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918306, encodeId=f0ea918306af, content=摄入维生素D可抑制子宫肌瘤的生长。<a href='/topic/show?id=53144518948' target=_blank style='color:#2F92EE;'>#子宫肌瘤#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45189, encryptionId=53144518948, topicName=子宫肌瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 10:26:41 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-08-17 zsyan
  3. [GetPortalCommentsPageByObjectIdResponse(id=1209433, encodeId=2586120943347, content=剂量是多少呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erFE1IgJcfnOGsibGrna95eBt7ELNXK85krdEJ0RAYjiaU11PyPj40c1BsktlfCfLH0n9jm99iahR06w/132, createdBy=05422454711, createdName=慧子, createdTime=Fri Apr 08 01:51:13 CST 2022, time=2022-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783562, encodeId=8d561e83562cd, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Aug 17 23:53:27 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773339, encodeId=a2d31e733398d, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Aug 25 17:53:27 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918409, encodeId=341991840944, content=已读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Wed Jan 20 14:51:22 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918306, encodeId=f0ea918306af, content=摄入维生素D可抑制子宫肌瘤的生长。<a href='/topic/show?id=53144518948' target=_blank style='color:#2F92EE;'>#子宫肌瘤#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45189, encryptionId=53144518948, topicName=子宫肌瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 10:26:41 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-08-25 xuyong536
  4. [GetPortalCommentsPageByObjectIdResponse(id=1209433, encodeId=2586120943347, content=剂量是多少呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erFE1IgJcfnOGsibGrna95eBt7ELNXK85krdEJ0RAYjiaU11PyPj40c1BsktlfCfLH0n9jm99iahR06w/132, createdBy=05422454711, createdName=慧子, createdTime=Fri Apr 08 01:51:13 CST 2022, time=2022-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783562, encodeId=8d561e83562cd, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Aug 17 23:53:27 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773339, encodeId=a2d31e733398d, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Aug 25 17:53:27 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918409, encodeId=341991840944, content=已读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Wed Jan 20 14:51:22 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918306, encodeId=f0ea918306af, content=摄入维生素D可抑制子宫肌瘤的生长。<a href='/topic/show?id=53144518948' target=_blank style='color:#2F92EE;'>#子宫肌瘤#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45189, encryptionId=53144518948, topicName=子宫肌瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 10:26:41 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-01-20 ms5000000518166734

    已读,受益匪浅

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1209433, encodeId=2586120943347, content=剂量是多少呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erFE1IgJcfnOGsibGrna95eBt7ELNXK85krdEJ0RAYjiaU11PyPj40c1BsktlfCfLH0n9jm99iahR06w/132, createdBy=05422454711, createdName=慧子, createdTime=Fri Apr 08 01:51:13 CST 2022, time=2022-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783562, encodeId=8d561e83562cd, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Aug 17 23:53:27 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773339, encodeId=a2d31e733398d, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Aug 25 17:53:27 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918409, encodeId=341991840944, content=已读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Wed Jan 20 14:51:22 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918306, encodeId=f0ea918306af, content=摄入维生素D可抑制子宫肌瘤的生长。<a href='/topic/show?id=53144518948' target=_blank style='color:#2F92EE;'>#子宫肌瘤#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45189, encryptionId=53144518948, topicName=子宫肌瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 10:26:41 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-01-20 Jessica

    摄入维生素D可抑制子宫肌瘤的生长。#子宫肌瘤#

    0

相关资讯

Clinical Nutrition: 妊娠前三个月维生素D状况与妊娠糖尿病之间的关系

妊娠期糖尿病(GDM)是怀孕期间最常见的并发症之一。从长远来看,它与许多不良妊娠,胎儿和新生儿结局以及母亲和儿童的风险增加有关。人们对维生素D及其在代谢性疾病发展中的潜在作用越来越感兴趣。

World Allergy Organ J:产前维生素D补充和儿童呼吸道健康:随机对照试验系统回顾和元分析

对母体维生素D状态和呼吸道过敏性疾病风险的观察性研究的系统回顾和元分析表明,母亲在怀孕期间补充维生素D可以降低后代复发性喘息或哮喘的风险。最近,有研究人员进行了随机对照试验的元分析,调查产前补充维生素

Clin Nutrition:维生素D缺乏与脑组织健康程度存在关联

有文献已经证实,维生素D缺乏与痴呆症的风险增加有关。

Dig Dis Sci:维生素D缺乏导致结肠局部肾素-血管紧张素系统的激活而加剧结肠炎症

炎性肠病(IBD)是人类胃肠道的慢性疾病,由克罗恩病(CD)和溃疡性结肠炎(UC)组成。

Nat Commun:孟德尔随机化分析评估维生素D与癌症易感性的关联性

维生素D是一种必需的脂溶性维生素,主要是由皮肤暴露于紫外线辐射所产生的。

Clin Nutrition: 25(OH)D的生物利用度与弥漫性大B细胞淋巴瘤患者的临床结局相关

我们已经知道,维生素D功能不足与多种癌症类型的临床结局较差有关。然而,其在弥漫性大B细胞淋巴瘤(DLBCL)患者中的作用仍不清楚。