JAMA:2013-18年间美国极早产儿出院存活率为78%,超过50%患儿在2岁时有中度以上神经发育障碍

2022-01-19 MedSci原创 MedSci原创

2013-18年间,美国孕22-28周出生的极早产儿出院存活率为78.3%,较2008-2012年数据提高了2%。在孕27周以下的早产儿中,2岁时再住院和神经发育障碍较为常见。


尽管近几十年来有所改善,但极早产儿的死亡率及后遗症风险仍较高。近日研究人员考察了2013-18年间,美国极早产儿在校正月龄22-26月时的生存率、住院率、护理需求、神经发育和功能结果。


研究在19个医疗中心开展,是尤妮斯·肯尼迪·施莱弗国家儿童健康和人类发展研究所新生儿研究的一部分。参与者为2013年1月1日至2018年12月31日期间出生的10877 名孕22-28周婴儿,在校正年龄22-26个月时完成了随访评估,与2008-2012年出生的足月新生儿进行比较。研究的主要终点为生存率和12种疾病发病率,包括坏死性小肠结肠炎、感染、颅内出血、早产儿视网膜病变和支气管肺发育不良。在校正年龄22-26个月时对婴儿进行12个健康和功能结果评估,包括神经发育、脑瘫、视力、听力、再住院和需要辅助设备等。
总计10877 名婴儿参与研究,其中女婴占49.0%,出院存活率为78.3%(8495/10848),较2008-2012年的76.0%有所增加(调整后差异,2.0%)。孕22周早产儿出院存活率为10.9%(60/549),孕28周早产儿出院存活率为94.0%(2267/2412)。接受积极治疗的孕22周早产儿婴儿出院存活率为30.0%(60/200),孕23周为55.8%(535/958)。出生胎龄越小,并发症住院率越高。总体而言,8.9%(890/9956)婴儿有坏死性小肠结肠炎,2.4%(238/9957)早发感染,19.9%(1911/9610)晚发感染,14.3%(1386/9705)有严重的颅内出血,12.8%(1099/8585)有严重的早产儿视网膜病变,8.0%(666/8305)有严重的支气管肺发育不良。2930名孕22-26周早产儿完成随访,其中2566例接受评估。经2年随访,8.4%(214/2555)儿童有中度至重度脑瘫,1.5%(38/2555)双侧失明,2.5%(64/2527)需要助听器或人工耳蜗,49.9%(1277/2561)再次住院,15.4%(393/2560)需要移动辅助或其他支持设备。2458名完成全面评估的婴儿中,48.7%(1198/2458)在随访时没有或有轻度的神经发育障碍,29.3%(709/2419)有中度的神经发育障碍,21.2%(512/2419)有严重的神经发育障碍。

早产儿的神经发育情况及存活率

2013-18年间,美国孕22-28周出生的极早产儿出院存活率为78.3%,较2008-2012年数据提高了2%。在孕27周以下的早产儿中,2岁时再住院和神经发育障碍较为常见。
原始出处:
Edward F. Bell et al.Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. JAMA,January 18, 2022。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
    2022-01-21 neurowu
  5. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2060827, encodeId=b76e206082e0d, content=<a href='/topic/show?id=c73f3e96355' target=_blank style='color:#2F92EE;'>#发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37963, encryptionId=c73f3e96355, topicName=发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Wed Dec 07 16:27:35 CST 2022, time=2022-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1863000, encodeId=ce52186300002, content=<a href='/topic/show?id=b5ca453451f' target=_blank style='color:#2F92EE;'>#存活率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45345, encryptionId=b5ca453451f, topicName=存活率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b3f89, createdName=daviiliu, createdTime=Fri Oct 14 09:27:35 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345651, encodeId=6227134565151, content=<a href='/topic/show?id=37c9e4238b9' target=_blank style='color:#2F92EE;'>#神经发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74238, encryptionId=37c9e4238b9, topicName=神经发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7532500500, createdName=12499e01m47暂无昵称, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347600, encodeId=eb1e134e6009c, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457055, encodeId=95d1145e055c2, content=<a href='/topic/show?id=09bd61685aa' target=_blank style='color:#2F92EE;'>#极早产儿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61685, encryptionId=09bd61685aa, topicName=极早产儿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=521c5837609, createdName=wmr113, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506422, encodeId=089d150642252, content=<a href='/topic/show?id=5ecce424448' target=_blank style='color:#2F92EE;'>#神经发育障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74244, encryptionId=5ecce424448, topicName=神经发育障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69ca9750324, createdName=fzwish20003, createdTime=Fri Jan 21 09:27:35 CST 2022, time=2022-01-21, status=1, ipAttribution=)]

相关资讯

盘点:极早产儿的那些相关研究

【1】Clin Nutr:极早产儿的ARA和DHA摄入量不足花生四烯酸(ARA)和二十二碳六烯酸(DHA)对大脑的发育至关重要,而且极度早产的婴儿可能面临这两种物质不足的现状。本研究的目的是量化,标准护理下早产儿出生后六周,所有来源ω-3和ω-6多不饱和脂肪酸(PUFA)的摄入量。此外,还对血液循环细胞因子和多不饱和脂肪酸含量之间的关系进行了探讨。本项单中心的纵向研究纳入了17例、孕周<28周

成功救治极早产儿一例

患儿,女,第5胎第1产,胎龄24+2周

JAMA Netw Open:中国新生儿网络(CHNN)第一份全年报告出炉,看看极早产儿的结局和预后怎样吧!

中国新生儿网络成立于2018年,维护着全国三级新生儿重症监护病房(NICD)极早产儿或极低出生体重儿的标准化国家临床数据库。

BMJ:极早产儿三级护理与围产期不良预后

研究认为,在极早产婴儿中,在非三级医院分娩和48小时内转院与在三级医院分娩相比,预后较差。研究人员建议建立完善的围产期三级医疗服务体系,而非产后紧急转院

Neurology:追踪13年(1月龄-13周岁),T1-W/T2-W 比值趋势与多维度智能发育相关,围产期危险因素增加偏离正常发育风险

极早产儿和多种已知的围产期危险因素与儿童和青春期白质区域T1-w/T2-w比值的长期降低有关。此外,13岁时T1-w/T2-w比值的增加与更好的运动和工作记忆功能有关,且VP和FT儿童存在发展差异。