Clin Exp Rheumatol:大动脉炎:相关的炎症性疾病

2020-03-30 xiangting MedSci原创

在约1/5的患者中,TAK确实与IBD、AS并存,而与BS并发的比率较低。

病例报告和系列报道表明,大动脉炎(TAK)可以与其他的炎性疾病共存。这里进行了一项正式研究,专门分析了一个三级中心随诊的大型TAK队列中这类炎症性疾病的发生率。

有238例被诊断为TAK的患者。其中19例死亡,18例失访,3例不愿回答问卷。剩余的198例患者(175F/23M)在门诊复诊。以标准化的形式询问患者是否也被诊断为炎症性肠病(IBD)、强直性脊柱炎(AS)、白塞氏综合症(BS)、自身免疫性疾病或其他炎症性疾病。还特别询问了是否存在皮肤粘膜病变、炎性眼病和炎性背痛。

确定了37例(19%)炎症性肠病(n=12,6%)、强直性脊柱炎(n=15、8%)或白塞氏综合症患者(n=10、5%)。13例患者(6.5%)有全身或局部自身免疫性疾病,9例(4.5%)有其他炎症性疾病。139例无其他伴随疾病的患者中,炎性背痛(n=49,35%)是最常见的症状,其次是复发性口腔溃疡(n=20,14%)、结节性红斑(n=17,12%)、关节炎(n=12,9%)、丘疹脓疱性病变(n=8,6%)和葡萄膜炎/巩膜炎(n=6,4%)。只有64例患者(32%)没有任何伴随疾病或特定的临床特征。

在约1/5的患者中,TAK确实与IBD、AS并存,而与BS并发的比率较低,至少在医院环境中如此。没有明确的时间模式。TAK患者脊柱炎性背痛的患病率高仍需要进一步考察。

原始出处:

S. Esatoglu. Takayasu's arteritis: associated inflammatory diseases. Clin Exp Rheumatol. March 2020.

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    2020-08-16 xsm927
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