Lancet Infect Dis:深圳391例新冠肺炎患者及密切接触者调查研究

2020-04-28 MedSci原创 MedSci原创

深圳新冠肺炎病例流行病学分析表明,隔离和接触追踪减少了社区内感染病例的时间,从而降低了疫情扩大风险

近日研究人员就深圳严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的传播监控情况进行了考察,包括疾病病程、传播和控制措施影响等关键指标。

从2020年1月14日到2月12日,深圳市疾病预防控制中心共发现391例SARS-CoV-2病例和1286例密切接触者。研究人员比较了通过症状监测和接触追踪确定的病例,并估计了从症状出现到确诊、隔离和入院的时间。研究人员还估计了疾病传播的指标,并分析了影响传播风险的因素。

病例年龄大于一般人群(平均45岁),男性(n=187)和女性(n=204)比例平衡。391例中有356例(91%)在最初评估时有轻度或中度临床症状。截至2020年2月22日,3例死亡,225例康复(中位康复时间21天)。病例在出现症状后平均4.6天被隔离,接触追踪减少了1.9天。与其他密切接触者相比,家庭接触者和与病例一起旅行的人受感染的风险更高(家庭接触者的比值比为6.27;与病例一起旅行的人的比值比为7.06)。家庭二次发病率为11.2%,儿童与成人一样易受感染(10岁以下儿童感染率为7.4%,人口平均为6.6%)。观察到的传播数(R)为0.4,平均连续间隔6.3天。

对深圳新冠肺炎病例流行病学分析表明,隔离和接触追踪减少了社区内感染病例的时间,从而降低了疫情扩大风险。

原始出处:

Qifang Bi et al. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study.Lancet Infect Dis. April 27,2020.

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    2020-09-19 howi
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    2020-04-28 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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    2020-04-28 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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