Stroke:缺血性卒中后的抑郁症状

2019-12-10 xing.T MedSci原创

由此可见,首次缺血性卒中后9个月,对于卒中幸存者和家庭照看人员抑郁症状高发较为常见,但有临床抑郁风险的抑郁症状发生率比之前报道的要低。患者和照看人员对抑郁症的预测因素有所不同,并且照看标准应纳入家庭照看因素。

缺血性卒中后持续性抑郁症在卒中幸存者中很常见,在家庭照看者中甚至更高,但很少有研究同时评估患者和照看者的抑郁症状水平及其预测因素。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,卒中幸存者及其家庭照看者(205个对子)来自国家REGARDS研究(卒中的地理和种族差异原因)以及CARES研究(照顾卒中恢复过来的成人研究)。研究人员也招募了人口统计学特征匹配的无卒中配对者(N=205)。通过电话采访参与者,并通过20个项目的流行病学研究中心抑郁量表来评估抑郁症状。

卒中幸存者(M=8.38)及其照看者(M=6.42)的抑郁症状显著升高于其匹配的对照者(分别为M=5.18和4.62)(Ps<0.03)。卒中幸存者报告的抑郁症状多于其照看者(P=0.008)。未发现种族或性别差异,但在患者和照看人员中发现了抑郁症状水平的差异预测。年龄较小、照看者年龄较大与卒中幸存者的更多的抑郁症状相关,而作为配偶的照看者,且报告护理积极性较少的照看者与照看者更多的抑郁症状有关。在这种基于人群的样本中,具有临床显著抑郁风险的照看者百分比(12%)低于之前从临床样本中获得看护者的研究。

由此可见,首次缺血性卒中后9个月,对于卒中幸存者和家庭照看人员抑郁症状高发较为常见,但有临床抑郁风险的抑郁症状发生率比之前报道的要低。患者和照看人员对抑郁症的预测因素有所不同,并且照看标准应纳入家庭照看因素。 

原始出处:

David L. Roth.et al.Depressive Symptoms After Ischemic Stroke Population-Based Comparisons of Patients and Caregivers With Matched Controls.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027039

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    2019-12-10 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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由此可见,年轻的缺血性卒中患者中有不到一半使用他汀类药物,其使用受年龄和危险因素的影响。服用他汀类药物与降低全因死亡率和卒中复发的风险独立相关。