JACC:经导管主动脉瓣置换术预后的性别差异

2019-11-27 不详 MedSci原创

经股路径主动脉瓣置换术(TAVR)是指南推荐用于治疗严重主动脉瓣狭窄的方法,然后不同性别可能会对预后有影响。本研究的目的旨在评估近10年不同性别对经股路径TAVR术后预后的影响。本研究纳入分析了2007-2018年CENTER数据库中12381名接受经股路径TAVR治疗的患者,其中58%为女性。与男性患者相比,女性患者的高血压和肾小球滤过率<30ml/min/1.73m2的发生率更高,但其他

经股路径主动脉瓣置换术(TAVR)是指南推荐用于治疗严重主动脉瓣狭窄的方法,然后不同性别可能会对预后有影响。本研究的目的旨在评估近10年不同性别对经股路径TAVR术后预后的影响。

本研究纳入分析了2007-2018年CENTER数据库中12381名接受经股路径TAVR治疗的患者,其中58%为女性。与男性患者相比,女性患者的高血压和肾小球滤过率<30ml/min/1.73m2的发生率更高,但其他传统心血管并发症发生率更低。术后30天卒中发生率和死亡率无性别差异。然而,女性患者的致死性或大出血风险会增高50%(6.7% vs. 4.4%; p < 0.01)。另外,在研究期间,与女性相比,男性的死亡率随着时间会逐渐降低。

研究结果显示,在接受经股路径的TAVR治疗患者中,男性和女性有相似的术后30天卒中发生率和死亡率,但是女性患者的术后致死性或大出血风险明显更高。


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    2019-11-30 hbwxf
  2. 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    2020-03-09 yxch48
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    2019-11-29 天地飞扬

    谢谢分享

    0

  4. 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  5. 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    2019-11-29 lsj631
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