PLos One:影响膝骨关节炎患者疼痛评分的社会心理和人口学因素

2018-04-12 xiangting MedSci原创

这项在一个大型多种族膝关节OA患者群中进行的研究表明,社会心理和社会人口因素可能是膝关节OA患者疼痛水平的重要决定因素。

膝关节骨关节炎(OA)患者的疼痛水平通常采用数字评分系统进行评估,但结果可能受到患者实际身体不适或疾病严重程度以外其他因素的影响,其中包括社会心理和人口学变量。这里探讨了355例膝骨关节炎患者中膝关节疼痛评分与社会心理、人口学、疾病和治疗变量之间的可能关系。

疼痛评估工具是0到10分的评定量表。从患者病历中回顾性获得人口学特征,体重指数(BMI),伴随疾病,违禁和处方药使用,饮酒,吸烟,OA的治疗和由Kellgren-Lawrence(KL)影像分级的膝关节OA严重程度。进行单因素和多因素分析以确定这些变量是否与报告的疼痛评分相关。

在单因素分析中,较高的疼痛评分与美洲土著或西班牙裔,较高的BMI,目前使用阿片类、抗抑郁或加巴喷丁类药物,抑郁,糖尿病,纤维肌痛,违禁药物使用,缺乏健康保险,吸烟,既往膝盖注射和由临床医生推荐进行膝关节手术显著相关。患者性别和KL等级均无相关性。在多因素分析中,抑郁症、目前使用阿片类药物以及美洲土著或西班牙裔与疼痛评分较高显著相关。

这项在一个大型多种族膝关节OA患者群中进行的研究表明,社会心理和社会人口因素可能是膝关节OA患者疼痛水平的重要决定因素。

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    2018-07-21 lisa438
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    2018-04-14 lmm397
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    2018-04-13 wxl882001

    学习一下

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