J Clin Periodontol:侵袭性牙周炎刮治和根面平整后龈下微生物群变化的研究

2018-03-27 MedSci MedSci原创

本研究旨在研究广泛性侵袭性牙周炎(GAgP)患者龈下菌群在刮治和根面平整(SRP)过程中的变化。

本研究旨在研究广泛性侵袭性牙周炎(GAgP)患者龈下菌群在刮治和根面平整(SRP)过程中的变化。

经过龈上刮治后,12名GAgP患者参加了这项纵向研究。3周内完成全口SRP并在6周后重新评估。从每个患者在SRP(治疗前组)和重新评估时(治疗后组)之前获得汇总的龈下样本(后-中间位点,后-颊侧位点,前-中间位点和前-颊侧位点)。DNA提取后进行16S rRNA PCR扩增并测序。

结果:在SRP下,龈下菌群的多样性是一致的,而属于Porphyromonas,Treponema和Fretibacterium的属水平生物标志物转化为放线菌,链球菌和嗜血杆菌。在网络分析中,在治疗前后的组中都确定了病原体相关和非病原体相关成分;病原体组分显着增加,而非病原体组分在治疗后减少。菌群也分布在治疗前的两个位点并限于治疗后病原体。

结论:刮治和根面平整减少了GAgP患者龈下菌群中的牙周病原体。然而,微生物群组成的变化表征为SRP后6周病原体相关组分的增加和非病原体相关组分的减少。

原始出处:

Guojing Liu, et al. Shift in the subgingival microbiome following scaling and root planing in generalized aggressive periodontitis. Journal of Clinical Periodontology. 2018 April. doi:10.1111/jcpe.12862

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    2018-11-27 feather89
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    2018-04-06 半夏微凉

    学习了谢谢分享

    0

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objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Mar 29 07:01:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300563, encodeId=7dcd3005635a, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Mar 28 21:37:59 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300471, encodeId=5a963004e14d, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Mar 28 08:23:44 CST 2018, time=2018-03-28, status=1, ipAttribution=)]
    2018-03-29 sunyl07
  5. 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  6. 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  7. 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  8. 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objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Mar 29 07:01:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300563, encodeId=7dcd3005635a, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Mar 28 21:37:59 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300471, encodeId=5a963004e14d, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Mar 28 08:23:44 CST 2018, time=2018-03-28, status=1, ipAttribution=)]
    2018-03-29 半夏微凉

    学习了谢谢分享

    0

  9. 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level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Mar 28 08:23:44 CST 2018, time=2018-03-28, status=1, ipAttribution=)]
    2018-03-28 1e1b8538m79(暂无匿称)

    不错的文章值得拥有

    0

  10. 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level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Mar 28 08:23:44 CST 2018, time=2018-03-28, status=1, ipAttribution=)]
    2018-03-28 龙胆草

    学习谢谢分享

    0

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本实验旨在调查Aggregatibacter actinomycetemcomitans血清型,牙周状态和冠状动脉疾病(CAD)之间的关联。

J Clin Periodontol:PPARγ对大鼠实验性牙周炎的双重作用

本实验旨在探讨PPARγ对实验性牙周炎大鼠炎症控制和骨重建的影响。

J Clin Periodontol:牙周预后方法的评估

该回顾性病例研究的目的是通过评估由牙周疾病引起的牙齿脱落(TLPD)的风险并评估牙周损害牙齿( PCT)的存活时间(ST)来评估指定牙周预后方法的有用性和情况。