Diabetes Care:儿童BMI、空腹血糖和胰岛素可预测成年2型糖尿病

2020-09-02 MedSci原创 MedSci原创

儿童BMI和血糖是成年T2DM的预测指标。从临床角度来看,这些易于应用的测量指标具有很好的前景。空腹胰岛素有可能成为T2DM额外的预测因素。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在评估儿童BMI、空腹血糖和胰岛素与成年2型糖尿病(T2DM)之间的关系。

研究人员使用了来自国际儿童血管队列联盟的数据,这些数据包括1970年代至1990年代获得的儿童(3至19岁)测量值;健康调查表,包括平均年龄40岁时获得的成年T2DM自我报告(发生年龄、服用药物情况)。

该研究的样本包含6738名参与者。在这些患者中,436名(6.5%)参与者报告在20至59岁(平均40.8岁)之间患有T2DM,其中,86%的患者报告服用了降糖药物。在对队列、国家、性别、种族、年龄和测量日期进行调整后,BMI和(年龄和性别标准化的)血糖与T2DM发生之间具有相关性。从30岁开始,儿童BMI和血糖水平的升高与T2DM风险增加有关。调整BMI和血糖后,胰岛素与成年T2DM之间存在正相关。

由此可见,儿童BMI和血糖是成年T2DM的预测指标。从临床角度来看,这些易于应用的测量指标具有很好的前景。空腹胰岛素有可能成为T2DM额外的预测因素。

原始出处:

Tian Hu,,et al.Childhood BMI and Fasting Glucose and Insulin Predict Adult Type 2 Diabetes: The International Childhood Cardiovascular Cohort (i3C) Consortium.Diabetes Care.2020.https://care.diabetesjournals.org/content/early/recent

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    2021-05-11 莉莉安 Lillian C.

    体重管理从娃娃开始

    0

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  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200903/8cb7d02b801f4b4188b479f048a1ea82/aadb84566e734c4f9911cbab85440546.jpg, createdBy=a81b5138261, createdName=1466e7edm56(暂无昵称), createdTime=Thu Sep 03 07:51:46 CST 2020, time=2020-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882293, encodeId=8c98882293dc, content=好奇假如在儿童时期胖,长大后减肥变瘦了呢?个人饮食习惯会随着知识的增长而改变的,感觉这个研究不靠谱。, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Sep 02 22:54:39 CST 2020, time=2020-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043311, encodeId=99ef1043311ff, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Sep 02 22:43:28 CST 2020, time=2020-09-02, status=1, ipAttribution=)]
    2021-04-25 baoya
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content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Sep 02 22:43:28 CST 2020, time=2020-09-02, status=1, ipAttribution=)]
    2020-09-03 14818eb4m67暂无昵称

    学习

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200903/8cb7d02b801f4b4188b479f048a1ea82/aadb84566e734c4f9911cbab85440546.jpg, createdBy=a81b5138261, createdName=1466e7edm56(暂无昵称), createdTime=Thu Sep 03 07:51:46 CST 2020, time=2020-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882293, encodeId=8c98882293dc, content=好奇假如在儿童时期胖,长大后减肥变瘦了呢?个人饮食习惯会随着知识的增长而改变的,感觉这个研究不靠谱。, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Sep 02 22:54:39 CST 2020, time=2020-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043311, encodeId=99ef1043311ff, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Sep 02 22:43:28 CST 2020, time=2020-09-02, status=1, ipAttribution=)]
    2020-09-03 1466e7edm56(暂无昵称)

    学习了

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200903/8cb7d02b801f4b4188b479f048a1ea82/aadb84566e734c4f9911cbab85440546.jpg, createdBy=a81b5138261, createdName=1466e7edm56(暂无昵称), createdTime=Thu Sep 03 07:51:46 CST 2020, time=2020-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882293, encodeId=8c98882293dc, content=好奇假如在儿童时期胖,长大后减肥变瘦了呢?个人饮食习惯会随着知识的增长而改变的,感觉这个研究不靠谱。, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Sep 02 22:54:39 CST 2020, time=2020-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043311, encodeId=99ef1043311ff, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Sep 02 22:43:28 CST 2020, time=2020-09-02, status=1, ipAttribution=)]
    2020-09-02 Jessica

    好奇假如在儿童时期胖,长大后减肥变瘦了呢?个人饮食习惯会随着知识的增长而改变的,感觉这个研究不靠谱。

    0

  10. 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content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Sep 02 22:43:28 CST 2020, time=2020-09-02, status=1, ipAttribution=)]
    2020-09-02 misszhang

    谢谢MedSci提供最新的资讯

    0

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