JACC:外周动脉疾病患者的他汀药使用情况

2020-07-17 MedSci原创 MedSci原创

外周动脉疾病(PAD)会增加动脉粥样硬化疾病(ASCVD)的发病风险。本研究的目的是比较PAD患者与冠心病(CHD)或脑血管病患者发生ASCVD事件的风险以及他汀类药物的使用情况。

外周动脉疾病(PAD)会增加动脉粥样硬化疾病(ASCVD)的发病风险。本研究的目的是比较PAD患者与冠心病(CHD)或脑血管病患者发生ASCVD事件的风险以及他汀类药物的使用情况。

本研究纳入分析了943232名年龄≥19岁的PAD、CHD或脑血管疾病患者,拥有1、2或3个疾病患者的ASCVD发病率分别是每1000人年40.8、68.9和119.5。单纯PAD、CHD和脑血管病患者的ASCVD事件发生率分别为34.7(95%CI:33.2-36.2)、42.2(95%CI:41.5-42.8)和38.9(95%CI:37.6-40.1)。在PAD和CHD、PAD和脑血管疾病以及CHD和脑血管病患者中,ASCVD事件发生率分别为72.8(95%CI:71.0-74.7)、63.9(95%CI:60.6-67.4)和67.9(95%CI:66.4-69.3)。单纯PAD患者他汀类药物使用率(33.9%)低于单纯脑血管病患者(43.0%)或单纯冠心病患者(51.7%)。

研究结果显示,尽管PAD患者发生ASCVD事件的风险较高,但与CHD或脑血管疾病患者相比,PAD患者服用他汀类药物的可能性较小

原始出处:

Lisandro D et al.Atherosclerotic Risk and Statin Use Among Patients With Peripheral Artery Disease.JACC.2020 July.

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    2020-08-15 hbwxf
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    2020-07-19 wangzheng00

    学习

    0

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