IJIR:阴茎假体术后疼痛在糖尿病患者中更严重么?

2020-05-16 AlexYang MedSci原创

充气阴茎假体(IPP)手术是药物难治性阴茎勃起功能障碍患者的一种有效、安全和令人满意的治疗选择。术后并发症包括感染、机械故障、侵蚀和疼痛。目前的文献表明需要一种更好的IPP术后疼痛治疗方法。

充气阴茎假体(IPP)手术是药物难治性阴茎勃起功能障碍患者的一种有效、安全和令人满意的治疗选择。术后并发症包括感染、机械故障、侵蚀和疼痛。目前的文献表明需要一种更好的IPP术后疼痛治疗方法。

最近,有研究人员探究了是否在糖尿病患者中IPP术后的疼痛所有差异。研究是一个单机构回顾性研究。研究发现,92(54.4%)名患者中具有糖尿病,其中96%的患者HbA1c>8。术后明显疼痛在HbA1c>8的患者中更加常见(41% vs 13%, p=0.047),并能导致更多的计划外就诊(27% vs 11%, p=0.042)。HbA1c>8且具有明显术后疼痛的患者更可能使用阿片类药物和加巴喷丁治疗(30% vs 14%, p=0.05)。糖尿病组和非糖尿病组之间的年龄没有统计学差异(均值59 vs 61,p=0.193)。西班牙裔和非裔美国人在糖尿病不良控制人群中占比87%,而白人占比13%(p<0.001)。控制不好的糖尿病存在更多的医学并存病(p<0.001)。逻辑回归中,HbA1c>8能够预测因疼痛的计划外就诊,OR为2.83(p=0.04)。IPP术后疼痛在糖尿病HbA1c>8的患者中更加剧烈,从而导致更多的术后30天计划外就诊。

最后,研究人员指出,具有显著术后疼痛的患者可以联用阿片类药物和加巴喷丁治疗。进一步的研究需要优化糖尿病患者IPP术后疼痛的管理。

原始出处:

Lael Reinstatler, Dayron Rodríguez, Briana Goddard et al. Postoperative penile prosthesis pain: is it worse in diabetic patients? IJIR. 23 April 2020

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    2020-05-18 dingxiaobo
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    2020-05-16 misszhang

    谢谢MedSci提供最新的资讯

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