JAHA:COVID-19患者心脏受累的临床特征和危险因素

2020-08-18 MedSci原创 MedSci原创

COVID-19患者心脏受累很常见。CRP水平升高、老年、潜在合并症和NCP严重程度是COVID-19患者心脏受累的主要危险因素。为了降低死亡率,在COVID-19治疗期间应更加注重心血管保护。

越来越多的研究表明,2019冠状病毒病(COVID-19)会累及心脏。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在调查COVID-19患者的临床特征,并进一步明确COVID-19患者心脏受累的危险因素。

研究人员分析了102名经实验室检查确诊并住院的COVID-19患者(52名女性,年龄19-87岁)数据,并收集了患者的流行病学和人口统计学特征、临床特征、常规实验室检查结果(包括心脏损伤生物标志物)、超声心动图、心电图、胸部影像学检查结果、治疗方法和临床结局。根据心脏标记物的不同水平,研究人员将患者分为有无心脏标记物异常的急性心脏损伤(ACI)组。

在这项研究中,102位患者中有72位(70.6%)患者存在心脏受累:心动过速(n=20)、心电图异常(n=23)、超声心动图结果异常(n=59)、心肌酶升高(n=55)和急性心肌损伤(n=9)。8名ACI患者年龄>60岁;其中有7名患者存在两种或多种潜在合并症(高血压、糖尿病、心血管疾病、慢性阻塞性肺疾病和慢性肾脏疾病)。ACI患者出现的新型冠状病毒性肺炎(NCP)比未确定性ACI患者严重得多(p<0.001)。多变量分析表明,C反应蛋白(CRP)水平、老年、NCP严重程度和潜在合并症是COVID-19患者心脏受累的危险因素。

由此可见,COVID-19患者心脏受累很常见。CRP水平升高、老年、潜在合并症和NCP严重程度是COVID-19患者心脏受累的主要危险因素。为了降低死亡率,在COVID-19治疗期间应更加注重心血管保护。

原始出处:

Huayan Xu.et al.Clinical Characteristics and Risk Factors of Cardiac Involvement in COVID‐19.J AM HEART ASSOC.2020.https://www.ahajournals.org/doi/abs/10.1161/JAHA.120.016807

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    2020-08-20 rayms

    新冠全身性疾病,每个组织器官病理越来越清晰,希望科学家早日攻克!

    0

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    2020-08-20 zhaohui6731
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    2020-08-18 1238d654m87暂无昵称

    0

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