Sci Rep:阴茎癌发病率更高的地区患者情况分析

2020-03-03 AlexYang MedSci原创

最近,有研究人员确定了巴西的马拉尼昂州中诊断为阴茎癌的患者的流行病学、组织病理学和临床特征情况,该地区是世界上发病率最高的地区。研究人员在2016年7月到2018年10月之间对116名阴茎癌患者进行了调查。大多数患者居住在乡村地区(57%),从事农业(58%),低水平教育或者没有受过教育(90%),结婚或者处于稳定的关系(74%)。平均年龄为60.4±16.51岁(范围为23-93岁)。研究发现,

最近,有研究人员确定了巴西的马拉尼昂州中诊断为阴茎癌的患者的流行病学、组织病理学和临床特征情况,该地区是世界上发病率最高的地区。

研究人员在2016年7月到2018年10月之间对116名阴茎癌患者进行了调查。大多数患者居住在乡村地区(57%),从事农业(58%),低水平教育或者没有受过教育(90%),结婚或者处于稳定的关系(74%)。平均年龄为60.4±16.51岁(范围为23-93岁)。研究发现,包皮过长占比66%,生殖器卫生不良或者中等占比73%,性传播感染历史占比55%以及恋兽癖占比60%。大多数患者第一次性接触年龄为16.2±2.8岁(10-25岁),75%的性伴侣大于6个月。最常见的初始症状为瘙痒症,大多数患者采取了等待治疗(治疗等待时间均值为18.9个月;范围2-84个月)。人乳头瘤病毒(HPV)相关的组织学特征在62%的患者中出现。大多数患者具有组织学II级或者III级(87%),不小于T2阶段的疾病(84%)和淋巴结疾病(42%)。在96%的患者中进行了阴茎切除术。

最后,研究人员指出,该地区阴茎癌的群体发生率最高,主要由低社会经济状态、高HPV感染发生率和包皮过长的特征。治疗的延迟与高晚期癌症和侵入性外科手术治疗有关。年轻患者的高发病率也是一个突出的特征。

原始出处:

Ciro Bezerra Vieira, Laisson Feitoza, Jaqueline Pinho et al. Profile of patients with penile cancer in the region with the highest worldwide incidence. Sci Rep. 19 Feb 2020

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    2020-03-05 dingxiaobo
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