JACC:PCI术后5年女性的主要不良心血管事件发生风险更高

2020-04-08 MedSci原创 MedSci原创

对经皮冠状动脉介入治疗(PCI)后与性别相关的预后研究报道存在相互矛盾的结果。本研究旨在探讨PCI术后5年心血管结局的性别相关风险。

对经皮冠状动脉介入治疗(PCI)后与性别相关的预后研究报道存在相互矛盾的结果。本研究旨在探讨PCI术后5年心血管结局的性别相关风险。

本研究收集了21个随机PCI试验的患者数据,并评估了5年内性别与主要不良心脏事件(心脏死亡、心肌梗死或缺血驱动的靶病变血管重建[ID-TLR])及其单个成分之间的关系。最终,共纳入分析了32877名患者,女性占27.8%。与男性相比,女性年龄更大,体重指数更高,高血压和糖尿病的发生率更高,手术或经皮血管重建的发生率更低。通过血管造影核心实验室分析,女性病变具有更小的病变血管直径和更短的病变长度。术后5年,与男性患者相比,女性患者的MACE、全因死亡率、心源性死亡率和ID-TLR的风险更高。多变量分析发现,女性是MACE和ID-TLR的独立预测危险因素,但不是全因死亡率和心源性死亡率的危险因素。

研究结果显示,经皮冠脉介入术后5年的女性主要不良心血管事件发生风险要高于男性。

原始出处:

Ioanna K et al.Long-Term Outcomes in Women and Men Following Percutaneous Coronary Intervention.JACC.2020 Apr.

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    2020-09-01 zxl736
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    2021-03-02 hbwxf
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    2020-05-09 148b0aa7m43(暂无昵称)

    应在同一年龄阶层进行比较才有意义

    0

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