JAHA:先天性心脏病手术后的慢性疾病负担

2020-04-23 xiangting MedSci原创

无论心脏病的严重程度如何,CHS后的慢性心脏和非心脏后遗症都很常见。

接受先天性心脏病手术(CHS)的患者中,术后疾病是越来越重要的结局指标。这项研究根据政府颁发的患者医疗特殊报销权,探讨了CHS术后的晚期疾病。

1953年至2009年间,芬兰共有10635名患者小于15岁时接受了CHS。排除早期死亡和精神残疾。非紫绀型和紫绀型心脏病分别被分为简单组和严重组。每名患者与4名年龄、性别、出生时间和医院地区匹配的对照者进行配对。芬兰社会保险机构提供了1966年至2012年授予的所有医疗特殊报销权数据。初次手术时开始随访,直至死亡、移民或2012年12月31日。

共有8623名患者符合纳入标准。随访率为99.9%。总计3750名患者(43%)需要针对慢性病的特殊报销权。心血管疾病是最常见的晚期疾病(28%),其次是阻塞性肺病(9%)、神经系统疾病(3%)和精神疾病(2%)。心衰(简单组风险比[HR], 56.3[95% CI, 35.4-89.7];严重组HR, 918.0[95% CI, 228.9-3681.7])和心律失常(简单组HR,11.0 [95%CI,7.1-17.0];严重组HR,248.0 [95%CI,61.3-1002.7])是最常见的心血管疾病。高血压在主动脉缩窄患者中很常见(13%;发病率风险比[RR],8.9;95%CI,7.5-10.7)。精神疾病在简单型心脏病患者中更常见,尤其是室间隔缺损。

无论心脏病的严重程度如何,CHS后的慢性心脏和非心脏后遗症都很常见,这强调了在CHS后对所有患者进行长期随访的重要性。

原始出处:

Alireza Raissadati. Chronic Disease Burden After Congenital Heart Surgery: A 47‐Year Population‐Based Study With 99% Follow‐Up. JAHA. 22 April 2020.

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    2020-04-25 一叶知秋
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    2020-04-25 huirong

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