PLOS ONE:产前暴露于二手烟对婴儿生长速度的影响

2019-06-23 海北 MedSci原创

现今,关于非吸烟孕妇暴露于二手烟(SHS)对于婴儿健康的影响的证据有限。 最近,研究人员评估了母亲产前接触SHS对婴儿生长率的影响,其次是对出生体重,出生长度和出生时头围的影响。

现今,关于非吸烟孕妇暴露于二手烟(SHS)对于婴儿健康的影响的证据有限。

最近,研究人员评估了母亲产前接触SHS对婴儿生长率的影响,其次是对出生体重,出生长度和出生时头围的影响。

在这个前瞻性队列中,研究人员研究了305对母婴。母亲填写了关于怀孕第3个月妊娠期SHS暴露的调查问卷。婴儿人体测量法在出生后第7天和出生后第1,2,4和6个月进行。线性混合建模和线性回归被用于计算前6个月的增长率。此外,研究人员还使用针对混杂因素调整的多元线性回归评估SHS暴露与生长速率和出生大小之间的关联,其中SHS包含香烟数量和组别(无暴露,SHS <23支香烟,SHS≥23支香烟)。

此次研究中,73名母亲未暴露,232名暴露。 SHS暴露(每根香烟)与体重,长度,头围和体重增长无关。然而,暴露于≥23支香烟/ d的母亲所生的婴儿的头围增长(-0.32 mm / m,95%CI -0.60,-0.03)低于未暴露母亲所生的婴儿。 SHS暴露(每支香烟)与出生体重,身长和头围无关,但暴露于≥23支香烟与出生时头围较低(-11.09 mm,-20.03,-2.16)有关。

因此,在非吸烟母亲中,严重的产前暴露于SHS会导致出生时新生儿头围较小,以及前六个月头围增加较少。

此外,该研究结果表明,在怀孕期间暴露于SHS与新生儿生长和出生体重的其他标志物之间没有明确的关系。


原始出处:

Soesanti F et al. Antenatal exposure to second hand smoke of non-smoking mothers and growth rate of their infants. SCIENCE, 2019; doi: 10.1371/journal.pone.0218577. eCollection 2019.


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    2020-02-18 yahu
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    2019-06-25 qilu_qi

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