Pediatr Allergy Immunol:蔬菜饮食模式能够预防轻度和永久过敏性鼻炎

2020-06-18 AlexYang MedSci原创

饮食对过敏性鼻炎(AR)的影响、儿童中AR的严重度和是否饮食对AR具有依赖于遗传易感性的影响均不清楚。最近,有研究人员根据遗传风险评分(GRS),在儿童中调查了饮食模式和AR的相关性以及饮食对AR的影

饮食对过敏性鼻炎(AR)的影响、儿童中AR的严重度和是否饮食对AR具有依赖于遗传易感性的影响均不清楚。最近,有研究人员根据遗传风险评分(GRS),在儿童中调查了饮食模式和AR的相关性以及饮食对AR的影响。

研究总共包括了435名7岁大的学龄儿童。研究人员使用饮食模式(蔬菜、糖和肉)和膳食发炎指数(DII)作为饮食参数。研究发现,蔬菜饮食包含了许多抗炎营养物质和更高的维他命D水平以及甘油三酯/HDL-胆固醇。蔬菜饮食(aOR, 95%CI=0.73, 0.58-0.94)和DII(1.13, 1.01-1.28)均与AR风险相关。特别的是,高蔬菜饮食能够导致更低风险的轻度和永久性AR(aOR, 95%CI=0.24, 0.10-0.56),而高的DII代表了更高的风险(2.33, 1.06-5.10)。蔬菜饮食对AR的保护性作用仅仅只在更低的GRS时存在(调整后p=0.018)。

最后,研究人员指出,高摄入抗炎营养物质和更高维生素D水平的蔬菜饮食模式与更低风险的轻度和永久性AR相关。上述益处受遗传因子修饰。

原始出处:

Hea Young Oh , So-Yeon Lee , Sungsu Jung et al. Vegetable Dietary Pattern May Protect Mild and Persistent Allergic Rhinitis Phenotype Depending on Genetic Risk in Schoolchildren. Pediatr Allergy Immunol. 10 Jun 2020.

 

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    2021-02-16 feather89
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    2020-06-20 膀胱癌
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