BMJ:健康生活方式可以延长寿命,减少晚年痴呆

2022-04-18 医诺维 医诺维

阿尔茨海默症(AD),俗称老年痴呆症,是一个具有高经济和社会负担的全球健康问题。全球约有5000万痴呆症病例,每年新增约有1000万例,在中国,有上千万患者,位居全球第一。尽管科学界投入了许多精力。

人们的生活品质越来越好,也越来越丰富,很多90后、00后的年轻人有熬夜、缺少锻炼、暴饮暴食等不良的生活方式,所以身体也提前进入了亚健康状态,这对今后的生活极其不利,身体是革命的本钱,健康才是王道。

阿尔茨海默症(AD),俗称老年痴呆症,是一个具有高经济和社会负担的全球健康问题。全球约有5000万痴呆症病例,每年新增约有1000万例,在中国,有上千万患者,位居全球第一。尽管科学界投入了许多精力,但目前仍然没有十分有效的治疗方案来预防或治愈。

2022年4月13日,美国芝加哥拉什大学医学中心的研究人员在《英国医学杂志》" BMJ "上发表了一篇题为" Healthy lifestyle and life expectancy with and without Alzheimer’s dementia: population based cohort study "的研究论文。

该研究发现,健康的生活方式可以延长预期寿命,重要的是,减少晚年患痴呆症的时长

在该研究中,研究人员分析了芝加哥健康与老龄化项目(CHAP)中2449名没有痴呆病史的参与者的数据,年龄在65岁及以上,所有参与者完成了详细的饮食和生活方式问卷。

根据研究人员定制的5个健康生活方式评分, 包括地中海-DASH饮食(富含全谷物、绿叶蔬菜和浆果的饮食,快餐/油炸食品和红肉含量低);晚年认知刺激活动;每周至少150分钟锻炼;不吸烟;低至中度饮酒。

对于每个生活方式因素,如果参与者符合健康标准,则获得1分,如果不符合,则为0分。将五个生活方式因素的得分相加,得出0-5的最终得分,分数越高表示生活方式越健康。

分析发现,拥有健康的生活方式可以延长3年预期寿命。

具体来讲,获得4-5分的女性和男性在65岁时的总预期寿命分别为24.2年和23.1年,而那些获得0-1分的女性和男性预期寿命较短,分别为21.1年和17.4年,平均缩短了3.1年。

生活得分与预期寿命和晚年痴呆关系

此外,拥有健康生活方式的人,晚年痴呆时间相对较短

具体来讲,对于拥有健康生活方式(4-5分)的女性和男性,剩余年份中分别有10.8%(2.6年)和6.1%(1.4年)患有阿尔茨海默病,而那些获得0-1分的女性和男性这一比例分别为19.3%(4.1年)和12.0%(2.1年)。

在85岁时,这些差异更加显着。

研究表明,健康的生活方式可以延长预期寿命,并且减少晚年患痴呆症的时间。

尽管如此,研究人员指出了其他一些限制,例如,生活方式是自我报告的,可能导致测量误差,并且本研究中提供的估计值不应在没有额外研究和验证的情况下推广到其他人群。

 

原始出处:

Healthy lifestyle and life expectancy with and without Alzheimer’s dementia: population based cohort study. BMJ, 2022.

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    2022-10-13 gaoxiaoe
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    2022-04-25 仇敏瑜

    非常受用!

    0

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    2022-04-19 weigq

    感觉不止3年。

    0

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    2022-04-16 neuro.Dr

    老年性痴呆,未来还是希望借助神经电生理吧,也许更为有效!

    0

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