JAHA:不同类型心脏手术后急性肾脏损伤的长期结局

2021-04-21 MedSci原创 MedSci原创

与其他心脏手术相比,主动脉手术引起D-AKI的发生率更高,但肾脏恢复更好,短期预后更好,长期透析的发生率更低。

需要透析的急性肾损伤(D-AKI)是血管外科手术的主要并发症,其会导致患者较差的预后。但是,尚未完全明确D‐AKI在不同类型心脏手术患者中的发生率和影响。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员从台湾国家健康保险研究数据库中确定了2004年7月1日至2013年12月31日期间接受心血管手术的患者,并将患者分为D-AKI组(n=3089)和非D-AKI组(n=42151)。该研究的结局是全因死亡率和主要不良肾脏事件。

研究人员发现D-AKI组的长期预后较非D-AKI组更差(严重不良肾脏事件的风险比[HR]为3.89;95%CI为3.79-3.99;全因死亡率HR为2.89;95%CI为2.81–2.98)。

接受主动脉手术的患者比其他类型的手术具有更高的D-AKI风险,但他们康复的几率更高。从D-AKI中恢复的患者的长期透析率在进行主动脉手术的患者中也最低。在伴有D‐AKI的所有类型心脏手术患者中,接受心脏瓣膜手术的患者全因死亡率最高(HR为6.04;95%CI为5.78-6.32)。

由此可见,与其他心脏手术相比,主动脉手术引起D-AKI的发生率更高,但肾脏恢复更好,短期预后更好,长期透析的发生率更低。

原始出处:

Jia‐Jin Chen.et al.Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.019718

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  5. 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  6. 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level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210420/978cb7a9bbc545b5b2a61273b2fd0754/498c401698c84f57b9a0a3efb1b8e4c0.jpg, createdBy=67a45482571, createdName=ms1000000056305151, createdTime=Wed Apr 21 22:55:46 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959195, encodeId=1936959195bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66085169796, createdName=146d43f7m73暂无昵称, createdTime=Wed Apr 21 21:57:14 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959189, encodeId=a9a2959189d2, content=学习了、涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=ms2000001051330459, createdTime=Wed Apr 21 21:48:17 CST 2021, time=2021-04-21, status=1, ipAttribution=)]
    2021-04-22 Doctoryangbai

    学习了,谢谢

    0

  7. 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level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210420/978cb7a9bbc545b5b2a61273b2fd0754/498c401698c84f57b9a0a3efb1b8e4c0.jpg, createdBy=67a45482571, createdName=ms1000000056305151, createdTime=Wed Apr 21 22:55:46 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959195, encodeId=1936959195bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66085169796, createdName=146d43f7m73暂无昵称, createdTime=Wed Apr 21 21:57:14 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959189, encodeId=a9a2959189d2, content=学习了、涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=ms2000001051330459, createdTime=Wed Apr 21 21:48:17 CST 2021, time=2021-04-21, status=1, ipAttribution=)]
    2021-04-22 我要当大牛

    在伴有D‐AKI的所有类型心脏手术患者中,接受心脏瓣膜手术的患者全因死亡率最高

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, createdName=Doctoryangbai, createdTime=Thu Apr 22 23:19:05 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959297, encodeId=949695929ee6, content=在伴有D‐AKI的所有类型心脏手术患者中,接受心脏瓣膜手术的患者全因死亡率最高, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/202404/7c0f0744e05f40309717bd3bd8e7d180-AwOc8oY53AN8.jpg, createdBy=bd115474335, createdName=我要当大牛, createdTime=Thu Apr 22 09:59:15 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959211, encodeId=2c9c9592118f, content=学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210420/978cb7a9bbc545b5b2a61273b2fd0754/498c401698c84f57b9a0a3efb1b8e4c0.jpg, createdBy=67a45482571, createdName=ms1000000056305151, createdTime=Wed Apr 21 22:55:46 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959195, encodeId=1936959195bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66085169796, createdName=146d43f7m73暂无昵称, createdTime=Wed Apr 21 21:57:14 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959189, encodeId=a9a2959189d2, content=学习了、涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=ms2000001051330459, createdTime=Wed Apr 21 21:48:17 CST 2021, time=2021-04-21, status=1, ipAttribution=)]
    2021-04-21 ms1000000056305151

    学习!

    0

  9. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, createdName=Doctoryangbai, createdTime=Thu Apr 22 23:19:05 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959297, encodeId=949695929ee6, content=在伴有D‐AKI的所有类型心脏手术患者中,接受心脏瓣膜手术的患者全因死亡率最高, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/202404/7c0f0744e05f40309717bd3bd8e7d180-AwOc8oY53AN8.jpg, createdBy=bd115474335, createdName=我要当大牛, createdTime=Thu Apr 22 09:59:15 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959211, encodeId=2c9c9592118f, content=学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210420/978cb7a9bbc545b5b2a61273b2fd0754/498c401698c84f57b9a0a3efb1b8e4c0.jpg, createdBy=67a45482571, createdName=ms1000000056305151, createdTime=Wed Apr 21 22:55:46 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959195, encodeId=1936959195bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66085169796, createdName=146d43f7m73暂无昵称, createdTime=Wed Apr 21 21:57:14 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959189, encodeId=a9a2959189d2, content=学习了、涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=ms2000001051330459, createdTime=Wed Apr 21 21:48:17 CST 2021, time=2021-04-21, status=1, ipAttribution=)]
    2021-04-21 146d43f7m73暂无昵称

    学习了,谢谢

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2193177, encodeId=ab7f21931e795, content=心, beContent=null, objectType=article, channel=null, level=null, likeNumber=12, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5d718627320, createdName=ms5000001346094455, createdTime=Thu Mar 14 14:42:36 CST 2024, time=2024-03-14, status=1, ipAttribution=广西), GetPortalCommentsPageByObjectIdResponse(id=2068833, encodeId=36a2206883383, content=<a href='/topic/show?id=9da3203482c' target=_blank style='color:#2F92EE;'>#不同类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20348, encryptionId=9da3203482c, topicName=不同类型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e7948, createdName=李研东, createdTime=Fri Sep 03 02:37:03 CST 2021, time=2021-09-03, status=1, ipAttribution=), 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, createdName=Doctoryangbai, createdTime=Thu Apr 22 23:19:05 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959297, encodeId=949695929ee6, content=在伴有D‐AKI的所有类型心脏手术患者中,接受心脏瓣膜手术的患者全因死亡率最高, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/202404/7c0f0744e05f40309717bd3bd8e7d180-AwOc8oY53AN8.jpg, createdBy=bd115474335, createdName=我要当大牛, createdTime=Thu Apr 22 09:59:15 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959211, encodeId=2c9c9592118f, content=学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210420/978cb7a9bbc545b5b2a61273b2fd0754/498c401698c84f57b9a0a3efb1b8e4c0.jpg, createdBy=67a45482571, createdName=ms1000000056305151, createdTime=Wed Apr 21 22:55:46 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959195, encodeId=1936959195bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66085169796, createdName=146d43f7m73暂无昵称, createdTime=Wed Apr 21 21:57:14 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959189, encodeId=a9a2959189d2, content=学习了、涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=ms2000001051330459, createdTime=Wed Apr 21 21:48:17 CST 2021, time=2021-04-21, status=1, ipAttribution=)]
    2021-04-21 ms2000001051330459

    学习了、涨知识了!

    0

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Sci Rep:术前住院时间延长与心脏手术后感染的风险升高相关

术前住院时间延长与心脏手术后院内感染的发生密切相关。

Sci Rep:心脏手术后心脏康复期间的炎性细胞因子及其与术后房颤的关联

这项研究结果会影响术后预防性抗心律失常的治疗策略。

JAHA:心脏手术后急性肾损伤的更好预测指标

这些数据表明,高AUC是体外循环后AKI的重要独立危险因素,可以考虑将其作为AKI的风险预测模型。

J Cardiothor Vas An:小儿心脏手术中脑电图监测下体外循环并深低温停循环的应用:一项系统回顾及Meta分析

心脏手术修复先天性心脏病对小儿发育中的大脑造成特定损伤。体外循环并深低温停循环(DHCA)是先天性心脏病修补术中一种简单有效的减少手术视野出血方法。然而,也有人担心,长时间的DHCA会增加神经系统损伤

Nutrition :营养不良提示心脏手术患者预后差!

营养物质是生命活动的物质基础,是维持生命体正常运转不可缺少的能量物质。近期Nutrition杂志发表的一项研究表示,患者的营养状况对预后影响显著。营养不足的程度越高,预后越差,尤其是心脏瓣膜病患者。