JADV:斑秃患者的心血管和代谢疾病患病率分析

2021-09-15 医路坦克 MedSci原创

斑秃(AA)是一种自身免疫性疾病,可出现无疤痕的脱发斑块。和其他自身免疫性疾病与心血管和代谢性疾病的风险增加相关,该文分析了AA型患者的心脏和代谢疾病的患病率。

斑秃(AA)是一种自身免疫性疾病,可出现无疤痕的脱发斑块。和其他自身免疫性疾病与心血管和代谢性疾病的风险增加相关,该文分析了AA型患者的心脏和代谢疾病的患病率。

在这项研究中,数据来自Explorys电子聚合数据库,由美国360家医院的5000多万名患者组成。3名AA患者使用SNOMED-CT术语“斑秃”(n=33,130名患者)进行识别。对照组为非斑秃患者(n=57,246,350例)。两组间比较采用皮尔逊χ2检验和Logistic回归分析。结果如下表:

 



在我们的斑秃患者中,除心肌梗死外,心脏和代谢紊乱的患病率更高。一项研究发现,斑秃患者发生急性心肌梗死和中风的几率降低。相反,另一项研究表明,在12年的随访中,斑秃患者患急性心肌梗死的风险增加。此外,还发现斑秃患者心肌肌钙蛋白I水平升高,这是一种心血管疾病生物标志物。与我们的研究结果相反,几项研究发现糖尿病患者中斑秃患病率降低。我们的数据集还描述了斑秃患者心房颤动的频率显著增加,这是以前没有讨论过的。还需要进一步的研究来证实这些发现,并检查成功治疗中AA的严重程度与代谢和心脏疾病患病率的相关性。

文献来源:Conic RRZ,  Chu S,  Tamashunas NL, Prevalence of cardiac and metabolic diseases among patients with alopecia areata.J Eur Acad Dermatol Venereol 2021 Feb;35(2)

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    2022-09-08 146480bem82暂无昵称

    斑秃(AA)是一种自身免疫性疾病,可出现无疤痕的脱发斑块。和其他自身免疫性疾病与心血管和代谢性疾病的风险增加相关,该文分析了AA型患者的心脏和代谢疾病的患病率。

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1247873, encodeId=9d5b124e87302, content=斑秃(AA)是一种自身免疫性疾病,可出现无疤痕的脱发斑块。和其他自身免疫性疾病与心血管和代谢性疾病的风险增加相关,该文分析了AA型患者的心脏和代谢疾病的患病率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05155126416, createdName=146480bem82暂无昵称, createdTime=Thu Sep 08 13:06:44 CST 2022, time=2022-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1243239, encodeId=02cf124323984, content=在我们的<a href='/topic/show?id=015c5e95173' target=_blank style='color:#2F92EE;'>#斑秃#</a>患者中,除<a href='/topic/show?id=b086512e33c' target=_blank style='color:#2F92EE;'>#心肌梗死#</a>外,心脏和<a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>紊乱的患病率更高。一项研究发现,斑秃患者发生急性心肌梗死和<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>的几率降低。相反,另一项研究表明,在12年的随访中,斑秃患者患急性心肌梗死的风险增加。此外,还发现斑秃患者心肌<a href='/topic/show?id=f4a581085cc' target=_blank style='color:#2F92EE;'>#肌钙蛋白#</a>I水平升高,这是一种心血管疾病生物标志物。与我们的研究结果相反,几项研究发现<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>患者中斑秃患病率降低。我们的数据集还描述了斑秃患者<a href='/topic/show?id=180251038d2' target=_blank style='color:#2F92EE;'>#心房颤动#</a>的频率显著增加,这是以前没有讨论过的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57951, encryptionId=015c5e95173, topicName=斑秃), TopicDto(id=51273, encryptionId=b086512e33c, topicName=心肌梗死), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢), TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中), TopicDto(id=81085, encryptionId=f4a581085cc, topicName=肌钙蛋白), TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=51038, encryptionId=180251038d2, topicName=心房颤动)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Mon Sep 05 02:34:07 CST 2022, time=2022-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1057401, encodeId=fd3f105e4018e, content=<a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>还需要进一步的研究来证实这些发现,并检查成功治疗中AA的严重程度与代谢和心脏疾病患病率的相关性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:05:36 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250756, encodeId=c26d1250e567d, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Fri Sep 17 02:36:24 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402021, encodeId=c5821402021c7, content=<a href='/topic/show?id=193025463d8' target=_blank style='color:#2F92EE;'>#代谢疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25463, encryptionId=193025463d8, topicName=代谢疾病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/F9591315BE4091482318EFFCD39C9D08/100, createdBy=bf9f2374681, createdName=windight, createdTime=Fri Sep 17 02:36:24 CST 2021, time=2021-09-17, status=1, ipAttribution=)]
    2022-09-05 小小医者

    在我们的#斑秃#患者中,除#心肌梗死#外,心脏和#代谢#紊乱的患病率更高。一项研究发现,斑秃患者发生急性心肌梗死和#卒中#的几率降低。相反,另一项研究表明,在12年的随访中,斑秃患者患急性心肌梗死的风险增加。此外,还发现斑秃患者心肌#肌钙蛋白#I水平升高,这是一种心血管疾病生物标志物。与我们的研究结果相反,几项研究发现#糖尿病#患者中斑秃患病率降低。我们的数据集还描述了斑秃患者#心房颤动#的频率显著增加,这是以前没有讨论过的。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1247873, encodeId=9d5b124e87302, content=斑秃(AA)是一种自身免疫性疾病,可出现无疤痕的脱发斑块。和其他自身免疫性疾病与心血管和代谢性疾病的风险增加相关,该文分析了AA型患者的心脏和代谢疾病的患病率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05155126416, createdName=146480bem82暂无昵称, createdTime=Thu Sep 08 13:06:44 CST 2022, time=2022-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1243239, encodeId=02cf124323984, content=在我们的<a href='/topic/show?id=015c5e95173' target=_blank style='color:#2F92EE;'>#斑秃#</a>患者中,除<a href='/topic/show?id=b086512e33c' target=_blank style='color:#2F92EE;'>#心肌梗死#</a>外,心脏和<a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>紊乱的患病率更高。一项研究发现,斑秃患者发生急性心肌梗死和<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>的几率降低。相反,另一项研究表明,在12年的随访中,斑秃患者患急性心肌梗死的风险增加。此外,还发现斑秃患者心肌<a href='/topic/show?id=f4a581085cc' target=_blank style='color:#2F92EE;'>#肌钙蛋白#</a>I水平升高,这是一种心血管疾病生物标志物。与我们的研究结果相反,几项研究发现<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>患者中斑秃患病率降低。我们的数据集还描述了斑秃患者<a href='/topic/show?id=180251038d2' target=_blank style='color:#2F92EE;'>#心房颤动#</a>的频率显著增加,这是以前没有讨论过的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57951, encryptionId=015c5e95173, topicName=斑秃), TopicDto(id=51273, encryptionId=b086512e33c, topicName=心肌梗死), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢), TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中), TopicDto(id=81085, encryptionId=f4a581085cc, topicName=肌钙蛋白), TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=51038, encryptionId=180251038d2, topicName=心房颤动)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Mon Sep 05 02:34:07 CST 2022, time=2022-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1057401, encodeId=fd3f105e4018e, content=<a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>还需要进一步的研究来证实这些发现,并检查成功治疗中AA的严重程度与代谢和心脏疾病患病率的相关性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:05:36 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250756, encodeId=c26d1250e567d, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Fri Sep 17 02:36:24 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402021, encodeId=c5821402021c7, content=<a href='/topic/show?id=193025463d8' target=_blank style='color:#2F92EE;'>#代谢疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25463, encryptionId=193025463d8, topicName=代谢疾病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/F9591315BE4091482318EFFCD39C9D08/100, createdBy=bf9f2374681, createdName=windight, createdTime=Fri Sep 17 02:36:24 CST 2021, time=2021-09-17, status=1, ipAttribution=)]
    2021-10-04 1def6e10m76(暂无匿称)

    #心血管#还需要进一步的研究来证实这些发现,并检查成功治疗中AA的严重程度与代谢和心脏疾病患病率的相关性。

    0

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