Boehringer Ingelheim与韩国Yuhan签订8.7亿美元合同,合作开发非酒精性脂肪性肝炎的双重激动剂

2019-07-03 不详 MedSci原创

Boehringer Ingelheim与韩国Yuhan签订价值高达8.70亿美元的合作协议,以开发GLP-1和FGF21的双重激动剂,用于治疗非酒精性脂肪性肝炎(NASH)和相关的肝脏疾病。该交易包括Boehringer Ingelheim的4000万美元的前期和近期支付,Yuhan还有资格获得高达8.3亿美元的潜在里程碑付款以及分层销售特许权使用费。

Boehringer Ingelheim与韩国Yuhan签订价值高达8.70亿美元的合作协议,以开发GLP-1和FGF21的双重激动剂,用于治疗非酒精性脂肪性肝炎(NASH)和相关的肝脏疾病。该交易包括Boehringer Ingelheim的4000万美元的前期和近期支付,Yuhan还有资格获得高达8.3亿美元的潜在里程碑付款以及分层销售特许权使用费。

Boehringer Ingelheim表示,针对NASH的一个靶点进行治疗无法在晚期患者中达到理想的疗效。双重激动剂通过同时减少肝细胞损伤和肝脏炎症,并发挥直接的抗纤维化作用,从而降低脂肪性肝炎。

Boehringer Ingelheim负责监督该制药创新部门的董事总经理Michel Pairet表示:"我们对这一新机遇感到非常兴奋,这增加了我们与Yuhan的长期合作伙伴关系,这种伙伴关系使我们更接近下一代NASH治疗方案。"

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    2019-10-30 qjddjq
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    2019-09-04 1de33e15m69(暂无匿称)

    现成的壳寡糖淘宝就能搜到,可惜大家被朗迪钙蒙蔽了双眼,中国人普遍不缺钙,可是造福人民的好药利民药为啥中央台一个都看不到,譬如降低化疗毒副作用的大连富生的参百益,心内科重症急救必备药2008诺贝尔奖NO一氧化氮欣舒口服液,击退各种不明感染退烧利器激活自身免疫提高巨噬细胞攻击力的β葡聚糖口服液,山西应该开发葶苈大枣泻肺汤的口服液,解决困扰临床多年的胸水腹水心包积液发高烧,限价不能超过板蓝根颗粒

    0

  6. 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  7. 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  8. 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  9. 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  10. 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    2019-07-04 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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