BMJ:饮食模式不会影响一般人群的血尿酸水平

2018-10-12 zhangfan MedSci原创

研究认为,饮食模式对一般人群血清尿酸水平的影响不显著

近日研究人员对膳食成分与血清尿酸水平之间的关系进行了系统考察。

16760名志愿者参与研究,参与者无肾病或痛风,也没有服用尿酸盐或利尿剂,对所有参与者进行血清尿酸含量测量、饮食调查、潜在混杂因素信息调整(性别、年龄、体重指数、每日平均卡路里摄入量、受教育年限、运动水平、吸烟状况和更年期状况),以及全基因组基因型分析。研究的主要终点为饮食与平均血清尿酸水平之间的关系。

研究发现7种食物与血清尿酸水平升高有关,包括啤酒、土豆、家禽、软饮料和肉类(牛肉、猪肉或羊肉);8种食物与降低血清尿酸水平有关,包括鸡蛋、花生、冷麦片、脱脂牛奶、奶酪、棕色面包、人造黄油和非柑橘类水果。建立在健康饮食指南基础上的饮食模式与血清尿酸水平负相关,但一般认为不健康的饮食对尿酸的影响不显著,尿酸升高饮食对血清尿酸变化≤0.3%,一般而言23.9%的尿酸水平变化是由于单核苷酸变异造成的。

研究认为,饮食模式对一般人群血清尿酸水平的影响不显著。

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    2020-08-28 14818eb4m67暂无昵称

    学习

    0

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    2019-04-10 gaoxiaoe
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    2018-10-14 quxin068
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