Eye Contact Lens:刚性透气性隐形眼镜对圆锥角膜患者内皮细胞的影响!

2018-01-31 cuiguizhong MedSci原创

土耳其伊斯坦布尔大学Cerrahpasa医学院眼科的Dogan C近日在Eye Contact Lens发表了一项重要的工作,他们在使用坚硬的透气性(RGP)隐形眼镜的患者和不使用隐形眼镜的健康人之间,比较了患圆锥角膜患者的角膜内皮细胞之间的不同。

土耳其伊斯坦布尔大学Cerrahpasa医学院眼科的Dogan C近日在Eye Contact Lens发表了一项重要的工作,他们在使用坚硬的透气性(RGP)隐形眼镜的患者和不使用隐形眼镜的健康人之间,比较了患圆锥角膜患者的角膜内皮细胞之间的不同。

这项研究中总共纳入了33名使用RGP隐形眼镜的圆锥角膜患者(组1),20名不使用隐形眼镜的圆锥角膜患者(组2)和40名健康对照者。使用非接触式镜面显微镜对所有患者的角膜内皮细胞的变化进行评估。在研究中,评价患者的内皮细胞密度(ECD)、变异系数(CV)、六角形细胞百分比(%HEX)和中央角膜厚度(CCT)。

结果他们发现,在1、2、3组中,平均ECD分别为2420.8±247、2579.5±240和2589.5±271个细胞每平方毫米,平均CV分别为357±9、34±7和34±6,平均六角形细胞百分比分别为54.3±13、59.1±14和57.4±10,平均CCT分别为508±33、504±43和561±34μm。 ECD、CV和六角形细胞百分比在个群体之间没有显着性差异。虽然在CCT方面,检测到组1-3和组2-3之间存在显着性差异(分别为P = 0.001和P = 0.004),但组1和组2之间没有观察到显着性差异。

尽管在中央角膜厚度(CCT)方面,组1和组2分别与正常人群之间存在显着差异,但是在其他参数方面没有检测到组间的显着差异。在这项研究中,作者认为,坚硬的透气性(RGP)隐形眼镜长期使用对角膜内皮细胞没有影响。

原文出处:

Dogan, C., et al., Effect of the Rigid Gas-Permeable Contact Lens Use on the Endothelial Cells in Patients With Keratoconus. Eye Contact Lens, 2018.

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    2018-12-11 grace5700
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topicName=TAC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b05b180, createdName=grace5700, createdTime=Tue Dec 11 06:40:00 CST 2018, time=2018-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736124, encodeId=c5c21e36124ab, content=<a href='/topic/show?id=05564121e2a' target=_blank style='color:#2F92EE;'>#圆锥角膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41217, encryptionId=05564121e2a, topicName=圆锥角膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2aeb34082524, createdName=lilili1115, createdTime=Tue Dec 18 17:40:00 CST 2018, time=2018-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349115, encodeId=56cd13491150b, content=<a href='/topic/show?id=4337909284a' target=_blank style='color:#2F92EE;'>#角膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90928, encryptionId=4337909284a, topicName=角膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560405, encodeId=a7ad156040591, content=<a href='/topic/show?id=4ff1e294238' target=_blank style='color:#2F92EE;'>#眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72942, encryptionId=4ff1e294238, topicName=眼镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=508115130308, createdName=zhangfenasdf, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566414, encodeId=9c7d156641416, content=<a href='/topic/show?id=4ff1e294238' target=_blank style='color:#2F92EE;'>#眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72942, encryptionId=4ff1e294238, topicName=眼镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=508115130308, createdName=zhangfenasdf, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589434, encodeId=0e6e158943439, content=<a href='/topic/show?id=fb149850ed9' target=_blank style='color:#2F92EE;'>#隐形眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98507, encryptionId=fb149850ed9, topicName=隐形眼镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284297, encodeId=4ef528429e6e, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Feb 02 00:18:01 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284156, encodeId=7fdf2841569f, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Feb 01 12:27:52 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
    2018-02-02 snowpeakxu
  5. [GetPortalCommentsPageByObjectIdResponse(id=2029844, encodeId=c5be2029844c5, content=<a href='/topic/show?id=fedde18245' target=_blank style='color:#2F92EE;'>#eye#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7182, encryptionId=fedde18245, topicName=eye)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/7F67E3BE360D6DD1D0A62E3E71E23CB6/100, createdBy=9d8a2500148, createdName=ms8888626721583891, createdTime=Sat Nov 10 07:40:00 CST 2018, time=2018-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033692, encodeId=981c2033692fa, content=<a href='/topic/show?id=fc431e0708f' target=_blank style='color:#2F92EE;'>#TAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17070, encryptionId=fc431e0708f, 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target=_blank style='color:#2F92EE;'>#眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72942, encryptionId=4ff1e294238, topicName=眼镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=508115130308, createdName=zhangfenasdf, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589434, encodeId=0e6e158943439, content=<a href='/topic/show?id=fb149850ed9' target=_blank style='color:#2F92EE;'>#隐形眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98507, encryptionId=fb149850ed9, topicName=隐形眼镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), 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time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2029844, encodeId=c5be2029844c5, content=<a href='/topic/show?id=fedde18245' target=_blank style='color:#2F92EE;'>#eye#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7182, encryptionId=fedde18245, topicName=eye)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/7F67E3BE360D6DD1D0A62E3E71E23CB6/100, createdBy=9d8a2500148, createdName=ms8888626721583891, createdTime=Sat Nov 10 07:40:00 CST 2018, time=2018-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033692, encodeId=981c2033692fa, content=<a href='/topic/show?id=fc431e0708f' target=_blank style='color:#2F92EE;'>#TAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17070, encryptionId=fc431e0708f, 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target=_blank style='color:#2F92EE;'>#眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72942, encryptionId=4ff1e294238, topicName=眼镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=508115130308, createdName=zhangfenasdf, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589434, encodeId=0e6e158943439, content=<a href='/topic/show?id=fb149850ed9' target=_blank style='color:#2F92EE;'>#隐形眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98507, encryptionId=fb149850ed9, topicName=隐形眼镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), 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time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2029844, encodeId=c5be2029844c5, content=<a href='/topic/show?id=fedde18245' target=_blank style='color:#2F92EE;'>#eye#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7182, encryptionId=fedde18245, topicName=eye)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/7F67E3BE360D6DD1D0A62E3E71E23CB6/100, createdBy=9d8a2500148, createdName=ms8888626721583891, createdTime=Sat Nov 10 07:40:00 CST 2018, time=2018-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033692, encodeId=981c2033692fa, content=<a href='/topic/show?id=fc431e0708f' target=_blank style='color:#2F92EE;'>#TAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17070, encryptionId=fc431e0708f, 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GetPortalCommentsPageByObjectIdResponse(id=284297, encodeId=4ef528429e6e, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Feb 02 00:18:01 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284156, encodeId=7fdf2841569f, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Feb 01 12:27:52 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
  8. 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target=_blank style='color:#2F92EE;'>#眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72942, encryptionId=4ff1e294238, topicName=眼镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=508115130308, createdName=zhangfenasdf, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589434, encodeId=0e6e158943439, content=<a href='/topic/show?id=fb149850ed9' target=_blank style='color:#2F92EE;'>#隐形眼镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98507, encryptionId=fb149850ed9, topicName=隐形眼镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Feb 02 11:40:00 CST 2018, time=2018-02-02, status=1, ipAttribution=), 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time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
    2018-02-02 飛歌

    厉害了我的哥

    0

  9. 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time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
    2018-02-01 天地飞扬

    了解一下.谢谢分享!

    0

  10. 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time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284055, encodeId=ef032840555f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu Feb 01 04:59:31 CST 2018, time=2018-02-01, status=1, ipAttribution=)]
    2018-02-01 秀红

    学习了

    0

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杜克大学医学院眼科系的Meyer JJ近日在Eye Contact Lens杂志上发表了他们近期的一项工作,他们研究了隐形眼镜(CL)磨损对白内障手术的生物学参数的影响,以及隐形眼镜(CL)裂缝是否可以减少人工晶状体(IOL)的预测误差。

三年不取隐形眼镜,懒到快失明

今年40岁的重庆人刘能(化名)在过去的三年里,竟然一天都没有取下隐形眼镜,导致突然失明。目前,通过医生的极力抢救治疗,刘能恢复了一定的视力,但再也无法回到从前。“他已经知错了,非常后悔。年轻人面子观也重,但我们家人愿意接受采访,希望能给所有戴隐形眼镜的人一个警示。”刘大爷说,他们家住南岸区,儿子刘能在沙坪坝区从事机械制造工作。3年前,近视的儿子在南岸区步行街一家眼镜店花了300多元,配了一副隐形眼

Parasitol Res:阿雷格里港(巴西南部)的棘阿米巴角膜炎病例研究

巴西南里奥格兰德州联邦大学寄生虫学系基础卫生科学研究所的Dos Santos DL近日在Parasitol Res发表了一项工作, 他们对阿雷格里港(巴西南部)的28例棘阿米巴角膜炎进行系统性回顾分析,对可能的危险因素和临床结果进行了详细的研究。

Eye Contact Lens:从角膜胶原蛋白膜释放莫西沙星!

美国匹兹堡匹兹堡医学院眼科眼科门诊部的Zhou S近日在Eye Contact Lens发表了他们的最近一项工作,他们比较了莫西沙星通过隐形眼镜(BCL)和角膜胶原膜(CSs)的扩散情况,研究了BCLs和CSs释放莫西沙星的相对能力,以及角膜胶原膜释放莫西沙星在临床中应用的潜力。

Eye Contact Lens:在激光原位角膜磨镶手术后佩戴角膜巩膜隐形眼镜对角膜生物力学参数影响!

西班牙巴伦西亚布哈索特瓦伦西亚大学物理学院光学与视觉科学系系的Montalt JC近日在Eye Contact Lens杂志上发表了他们近期的一项工作,他们在激光原位角膜磨镶术(LASIK)后患有不规则角膜的患者中研究了其佩戴角膜巩膜隐形眼镜(CScL)的角膜生物力学参数。

游泳戴隐形眼镜致视力严重受损,夏季游泳如何防眼病

一男性青年去欢乐谷玩,游泳戴着隐形眼镜,眼睛不适后没有注意及时就医,直至回家后发现眼睛红得厉害,来就医时角膜已经发炎混浊,视力严重受损。每年夏季医院都会接诊不少游泳导致眼部疾病的病例。复旦大学附属眼耳鼻喉科医院眼科主治医师、哈佛大学医学院博士后洪佳旭医生近日就接诊了上述这例令其印象深刻的案例。夏季是各种病原微生物快速生长和传播的季节,是各种眼表疾病高发的季节,平均感染率是冬季的两倍,尤其是公共游泳