J Rheumatol:吸烟和肥胖对原发性干燥综合征患病风险的影响

2019-01-16 xiangting MedSci原创

在这项基于人群的研究中,目前吸烟与病例/对照状态呈负相关,然而体重指数与病例/对照状态没有任何关联。

这项研究旨在探讨吸烟和肥胖在原发性干燥综合征(pSS)中的作用。

研究人员将2000年至2015年间奥姆斯特德县(明尼苏达州,美国)诊断为pSS的居民(n=106)与3组无pSS的对照进行比较,这些对照是从奥姆斯特德县居民中随机选出的,并根据年龄和性别进行匹配。

目前吸烟者是pSS患者的可能性较低(OR 0.34,95%CI 0.14-0.85),然而与从不吸烟者相比,既往吸烟与病例/对照状态无关联(OR 1.27,95%CI 0.80-2.03)。吸烟状况与抗核抗体、抗SSA、抗SSB或类风湿因子阳性无关(p>0.05)。肥胖的OR为0.79(95%CI 0.48-1.30)。

在这项基于人群的研究中,目前吸烟与病例/对照状态呈负相关,然而体重指数与病例/对照状态没有任何关联。

原始出处:

Luisa Servioli. Association of Smoking and Obesity on the Risk of Developing Primary Sjogren Syndrome: A Population-based Cohort Study. J Rheumatol. 15 January 2019.

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    干燥综合症发病与感染溶血性链球菌有关

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