Heart:COVID-19大流行对STEMI患者死亡率的影响

2020-12-20 MedSci原创 MedSci原创

STEMI患者入院显著减少,与住院死亡率的显著增加无关。发病率降低的原因仍是推测性的。但是,分析的数据表明,在大多数国家中,大流行期间一直保持了对这些患者的紧急和及时医疗服务。

自从SARS-CoV-2疫情爆发以来,医院报告称ST段抬高型心肌梗死(STEMI)入院患者的数量有所下降,这表明SARS-CoV-2大流行可能使患者无法寻求紧急医疗服务。但是,研究之间的结果和死亡率数据并不一致。

近日,心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员检索了PubMed、Embase和Web of Science数据库确定了报道COVID-19大流行之前和期间入院的STEMI患者的死亡率的文献,并进行荟萃分析。此外,评估了院前和院内的延迟时间。

研究人员评估了10项研究,总共50123名患者的结果。研究表明尽管在COVID-19大流行期间STEMI患者的总体入院率显著下降(发生率比=0.789,95%CI为0.730至0.852,I2=77%,p<0.01),但与爆发前入院的STEMI患者相比,住院死亡率没有显著差异(OR=1.178,95%CI为0.926到1.498,I2=57%,p=0.01)。从症状发作到首次就医的时间相似(平均差(MD)=33.4 min,95%CI为-10.2至77.1,I2=88%,p<0.01),而大流行期间从就诊到开始球囊治疗的时间显著延长(MD=7.3 min,95%CI为3.0至11.7,I2=95%,p<0.01)。

由此可见,STEMI患者入院显著减少,与住院死亡率的显著增加无关。发病率降低的原因仍是推测性的。但是,分析的数据表明,在大多数国家中,大流行期间一直保持了对这些患者的紧急和及时医疗服务。

原始出处:

Manuel Rattka.et al.Effect of the COVID-19 pandemic on mortality of patients with STEMI: a systematic review and metaanalysis.heart.2020.https://heart.bmj.com/content/early/2020/12/16/heartjnl-2020-318360

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    2020-12-22 zhaojie88
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    2020-12-22 slcumt
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    2020-12-20 ms1000001516041629

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