Pacing Clin Electrophysiol:安贞医院马长生等研究称,零射线消融为孕妇带来希望!

2019-10-24 朱朱 中国循环杂志

北京安贞医院马长生教授团队报告,临床上,特发性持续性快速性心律失常在心脏结构正常的孕妇中并不少见,患病率为1.2%。

北京安贞医院马长生教授团队报告,临床上,特发性持续性快速性心律失常在心脏结构正常的孕妇中并不少见,患病率为1.2%。

导管射频消融是治疗持续性快速性心律失常的一种有效、可靠的方法,但对于孕妇来说,由于射线暴露,这种手术治疗很少施行。

该团队在零射线暴露的情况下,为28名药物难治性和频繁发作的严重心律失常孕妇安全地施行了导管射频消融治疗,且效果不错。

研究者指出,目前,药物治疗是孕妇心律失常的一线治疗。零透视下导管消融治疗可作为持续性快速性心律失常孕妇的一种挽救治疗,但必须是药物难治性的持续性快速性心律失常,其长期有效性和安全性还需要在更大规模队列中进一步验证。

该研究覆盖北京安贞医院于2015年至2018年所有妊娠相关的住院记录,在12 584名孕妇中,156名(1.2%)诊断存在持续性快速性心律失常,但心脏结构均正常,室性早搏和阵发性室上性心动过速是最常见的类型。

其中,28名孕妇(21~37岁)因为药物治疗无效和频繁发作的严重心律失常而接受导管消融治疗。这些孕妇均是在零透视的情况下成功接受手术治疗,平均手术时间为72.4分钟。11名孕妇在心腔内超声心动图导管的指导下进行经房间隔穿刺。

这些接受导管消融治疗的孕妇平均历经37周妊娠后,产下了28名健康婴儿。分娩期间未出现心脏相关不良事件。

在后续的随访期间,所有孕妇均未再出现心律失常,所有婴儿发育良好。

另外128名未接受导管射频消融的孕妇中,47名接受短期的抗心律失常治疗,其中68.1%应用β受体阻滞剂,40人在分娩时停用抗心律失常治疗。

3名孕妇在分娩时即便应用抗心律失常药物,仍出现了急性发作或持续的快速性心律失常。1名孕妇出现胎儿窘迫,因此接受紧急剖腹产手术。

5名孕妇因非心脏原因早期终止妊娠。其余未进行导管射频消融治疗的孕妇平均历经38周妊娠,产下124名婴儿,早产儿和低出生体重儿分别占8.6%和7.0%。

原始出处:Li MM1, Sang CH1, Jiang CX1, et al. Maternal arrhythmia in structurally normal heart: Prevalence and feasibility of catheter ablation without fluoroscopy. Pacing Clin Electrophysiol. 2019 Oct 17.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1994214, encodeId=809d199421437, content=<a href='/topic/show?id=7841458350f' target=_blank style='color:#2F92EE;'>#安贞医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45835, encryptionId=7841458350f, topicName=安贞医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 08 05:12:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773819, encodeId=27c71e73819d2, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Tue Jun 02 10:12:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1788928, encodeId=ccba1e889282a, content=<a href='/topic/show?id=866d1421e4c' target=_blank style='color:#2F92EE;'>#Physio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14217, encryptionId=866d1421e4c, topicName=Physio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 01 16:12:00 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421790, encodeId=f18e1421e90d6, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Fri Oct 25 16:12:00 CST 2019, time=2019-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028686, encodeId=86812028686c0, content=<a href='/topic/show?id=8386101493df' target=_blank style='color:#2F92EE;'>#马长生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101493, encryptionId=8386101493df, topicName=马长生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Nov 07 19:12:00 CST 2019, time=2019-11-07, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1994214, encodeId=809d199421437, content=<a href='/topic/show?id=7841458350f' target=_blank style='color:#2F92EE;'>#安贞医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45835, encryptionId=7841458350f, topicName=安贞医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 08 05:12:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773819, encodeId=27c71e73819d2, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Tue Jun 02 10:12:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1788928, encodeId=ccba1e889282a, content=<a href='/topic/show?id=866d1421e4c' target=_blank style='color:#2F92EE;'>#Physio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14217, encryptionId=866d1421e4c, topicName=Physio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 01 16:12:00 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421790, encodeId=f18e1421e90d6, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Fri Oct 25 16:12:00 CST 2019, time=2019-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028686, encodeId=86812028686c0, content=<a href='/topic/show?id=8386101493df' target=_blank style='color:#2F92EE;'>#马长生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101493, encryptionId=8386101493df, topicName=马长生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Nov 07 19:12:00 CST 2019, time=2019-11-07, status=1, ipAttribution=)]
    2020-06-02 kalseyzl
  3. [GetPortalCommentsPageByObjectIdResponse(id=1994214, encodeId=809d199421437, content=<a href='/topic/show?id=7841458350f' target=_blank style='color:#2F92EE;'>#安贞医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45835, encryptionId=7841458350f, topicName=安贞医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 08 05:12:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773819, encodeId=27c71e73819d2, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Tue Jun 02 10:12:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1788928, encodeId=ccba1e889282a, content=<a href='/topic/show?id=866d1421e4c' target=_blank style='color:#2F92EE;'>#Physio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14217, encryptionId=866d1421e4c, topicName=Physio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 01 16:12:00 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421790, encodeId=f18e1421e90d6, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Fri Oct 25 16:12:00 CST 2019, time=2019-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028686, encodeId=86812028686c0, content=<a href='/topic/show?id=8386101493df' target=_blank style='color:#2F92EE;'>#马长生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101493, encryptionId=8386101493df, topicName=马长生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Nov 07 19:12:00 CST 2019, time=2019-11-07, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1994214, encodeId=809d199421437, content=<a href='/topic/show?id=7841458350f' target=_blank style='color:#2F92EE;'>#安贞医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45835, encryptionId=7841458350f, topicName=安贞医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 08 05:12:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773819, encodeId=27c71e73819d2, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Tue Jun 02 10:12:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1788928, encodeId=ccba1e889282a, content=<a href='/topic/show?id=866d1421e4c' target=_blank style='color:#2F92EE;'>#Physio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14217, encryptionId=866d1421e4c, topicName=Physio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 01 16:12:00 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421790, encodeId=f18e1421e90d6, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Fri Oct 25 16:12:00 CST 2019, time=2019-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028686, encodeId=86812028686c0, content=<a href='/topic/show?id=8386101493df' target=_blank style='color:#2F92EE;'>#马长生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101493, encryptionId=8386101493df, topicName=马长生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Nov 07 19:12:00 CST 2019, time=2019-11-07, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1994214, encodeId=809d199421437, content=<a href='/topic/show?id=7841458350f' target=_blank style='color:#2F92EE;'>#安贞医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45835, encryptionId=7841458350f, topicName=安贞医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 08 05:12:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773819, encodeId=27c71e73819d2, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Tue Jun 02 10:12:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1788928, encodeId=ccba1e889282a, content=<a href='/topic/show?id=866d1421e4c' target=_blank style='color:#2F92EE;'>#Physio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14217, encryptionId=866d1421e4c, topicName=Physio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 01 16:12:00 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421790, encodeId=f18e1421e90d6, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Fri Oct 25 16:12:00 CST 2019, time=2019-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028686, encodeId=86812028686c0, content=<a href='/topic/show?id=8386101493df' target=_blank style='color:#2F92EE;'>#马长生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101493, encryptionId=8386101493df, topicName=马长生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Nov 07 19:12:00 CST 2019, time=2019-11-07, status=1, ipAttribution=)]

相关资讯

Sci Rep:小剂量的胸部放射引起循环系统疾病的风险不可忽视

目前很多报道表明,大剂量的电离辐射可导致循环系统疾病。但是暴露于低剂量(<0.5Gy)射线的风险仍不清楚。

Science新闻:去火星你的大脑会发生什么

NASA打算在2030年将第一批宇航员送到火星,这些宇航员将会好几年暴露在宇宙射线之下。科学家们日前发现,宇宙射线的高能粒子会改变神经元形态,影响宇航员的记忆和其他认知能力。Science网站特别刊文对此进行了介绍。宇宙射线一直是困扰星际旅行的大问题,NASA(和一些科幻小说家)花了大量的时间探索相应的保护措施,比如说用缓冲液环绕宇宙飞船。不过迄今为止,人们并不清楚宇宙射线的具体危害。人们很难直接

GW-ICC2017︱绿色电生理技术:不穿铅衣做手术,医生患者都受益

介入手术已经成为心脏疾病的最有效根治手段之一,但长期以来介入手术都必须要在射线指引下才能开展。射线对于身体的危害众所周知,做心脏介入手术必须要吃射线吗?2017年 10月12日主题为“心随绿动,健康同行”的新闻发布会在京召开,中国绿色电生理联盟核心团队就这个问题作了全面详细的回答。完全零射线射频消融手术(T3D绿色电生理技术)未来将有望让医生“无铅无挂”,让患者的健康不再受到射线损害,尤其是既往射

BMJ:接触射线可增加乳腺癌风险(GENE-RAD-RISK研究)

  近期,GENE-RAD-RISK研究表明,接触诊断性放射可增加BRCA1/2基因变异携带者罹患乳腺癌的风险。该研究是由荷兰癌症研究所发起的横跨欧洲三国(法国、英国、荷兰)的大型回顾性队列研究。旨在估计乳腺癌的风险与BRCA1/2基因突变携带者接受诊断性辐射的相关性。文章发表在BMJ上。   2006年至2009年间,研究人员共录入了1993例女性BRCA1/2基因突变携带者。试验主要通过权重

零射线!北京儿童医院首开儿科绿色射频消融

零射线!北京儿童医院首开儿科绿色射频消融